Pre-emptive analgesia efficacy of piroxicam versus tramadol in oral surgery.

Autor:	Muthuluri T; Department of Oral & Maxillofacial Surgery, SVS Institute of Medical & Dental Sciences, Mehaboobnagar, TG, India., Chandrupatla SG; Public Health Dentist, Ibn Sina Foundation, Houston, Texas, USA., Rajan R; Department of Oral & Maxillofacial Surgery, SVS Institute of Medical & Dental Sciences, Mehaboobnagar, TG, India., Reddy VV; Department of Oral & Maxillofacial Surgery, SVS Institute of Medical & Dental Sciences, Mehaboobnagar, TG, India., Jhawar DK; Department of Oral & Maxillofacial Surgery, SVS Institute of Medical & Dental Sciences, Mehaboobnagar, TG, India., Potturi A; Department of Oral & Maxillofacial Surgery, SVS Institute of Medical & Dental Sciences, Mehaboobnagar, TG, India.
Jazyk:	angličtina
Zdroj:	Journal of dental anesthesia and pain medicine [J Dent Anesth Pain Med] 2022 Dec; Vol. 22 (6), pp. 443-450. Date of Electronic Publication: 2022 Nov 24.
DOI:	10.17245/jdapm.2022.22.6.443
Abstrakt:	Background: This double-blind randomized controlled trial (RCT) was conducted to evaluate the pre-emptive analgesia and anti-inflammatory efficacy of piroxicam compared with tramadol in patients undergoing oral surgery. Methods: Seventy-eight patients who required extraction of impacted mandibular third molars were randomized into three treatment groups of 26 patients each: group I received 100 mg of tramadol, group II received 20 mg of piroxicam, and group III received a placebo. Drugs were administered intramuscularly 30 min prior to the extraction procedure. Results: Pain intensity, time to first analgesic administration, total analgesic consumption, facial edema, and trismus were the outcomes of interest. The group receiving 20 mg of piroxicam showed significantly lower pain intensity, increased time to first analgesic, and reduced edema from preoperative to postoperative day seven than those in the tramadol and placebo groups. Conclusion: The findings of this study showed that piroxicam had significant pain relief efficacy after third molar surgery compared with that in tramadol. Competing Interests: CONFLICTS OF INTEREST: The authors declare no conflicts of interest. (Copyright © 2022 Journal of Dental Anesthesia and Pain Medicine.)
Databáze:	MEDLINE
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