Hypertriglyceridemia with pancreatitis at disease onset in systemic lupus erythematosus.

Autor:	Atlani M; Nephrology, AIIMS Bhopal, Bhopal, Madhya Pradesh, India mahendra.nephro@aiimsbhopal.edu.in., Bhatt GC; Division of Pediatric Nephrology, Department of Pediatrics, AIIMS Bhopal, Bhopal, Madhya Pradesh, India., Tarachandani D; General Medicine, All India Institute of Medical Science-Bhopal, Bhopal, Madhya Pradesh, India., Charan V; Medicine, AIIMS Bhopal, Bhopal, Madhya Pradesh, India.
Jazyk:	angličtina
Zdroj:	BMJ case reports [BMJ Case Rep] 2023 Jan 04; Vol. 16 (1). Date of Electronic Publication: 2023 Jan 04.
DOI:	10.1136/bcr-2022-250166
Abstrakt:	Systemic lupus erythematosus (SLE) is an autoimmune disease characterised by the presence of several autoantibodies, immune complex formation and multiple organ system involvement. SLE has a wide range of manifestations involving nearly all organ systems. Hypertriglyceridemia (HTG) in SLE is a well-established and a common abnormality, which is generally mild and not included in the diagnostic criteria of SLE. HTG as the initial manifestation of SLE in adult patients in association with acute pancreatitis at levels below 1000 mg/dL has not been previously reported. Here, we report a case of rare presentation of moderate HTG (TG-869 mg/dL) with pancreatitis at disease onset in an adult women which later proved to be due to SLE and progressed to levels of severe HTG during the course of illness. The patient was successfully treated with plasma exchanges and cyclophosphamide. Competing Interests: Competing interests: None declared. (© BMJ Publishing Group Limited 2023. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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