Unequal Recovery in Colorectal Cancer Screening Following the COVID-19 Pandemic: A Comparative Microsimulation Analysis.

Autor:	de Lima PN; Engineering and Applied Sciences Department, RAND Corporation, Santa Monica, California, USA., van den Puttelaar R; Department of Public Health, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, Netherlands., Hahn AI; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Harlass M; Department of Public Health, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, Netherlands., Collier N; Decision and Infrastructure Sciences Division, Argonne National Laboratory, Lemont, Illinois, USA., Ozik J; Decision and Infrastructure Sciences Division, Argonne National Laboratory, Lemont, Illinois, USA., Zauber AG; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Lansdorp-Vogelaar I; Department of Public Health, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, Netherlands., Rutter CM; Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA.
Jazyk:	angličtina
Zdroj:	MedRxiv : the preprint server for health sciences [medRxiv] 2022 Dec 26. Date of Electronic Publication: 2022 Dec 26.
DOI:	10.1101/2022.12.23.22283887
Abstrakt:	The aftermath of the initial phase of the COVID-19 pandemic may contribute to the widening of disparities in access to colorectal cancer (CRC) screening due to differential disruptions to CRC screening. This comparative microsimulation analysis uses two CISNET CRC models to simulate the impact of ongoing screening disruptions induced by the COVID-19 pandemic on long-term CRC outcomes. We evaluate three channels through which screening was disrupted: delays in screening, regimen switching, and screening discontinuation. The impact of these disruptions on long-term colorectal cancer (CRC) outcomes was measured by the number of Life-years lost due to CRC screening disruptions compared to a scenario without any disruptions. While short-term delays in screening of 3-18 months are predicted to result in minor life-years loss, discontinuing screening could result in much more significant reductions in the expected benefits of screening. These results demonstrate that unequal recovery of screening following the pandemic can widen disparities in colorectal cancer outcomes and emphasize the importance of ensuring equitable recovery to screening following the pandemic.
Databáze:	MEDLINE
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