Acute posterior multifocal placoid pigment epitheliopathy following COVID-19 infection.

Autor: Fischer NA; Department of Ophthalmology and Visual Sciences, University of Alabama at Birmingham 1720 University Boulevard Birmingham, AL 35294-0099, USA., Wann RC; Department of Ophthalmology and Visual Sciences, University of Alabama at Birmingham 1720 University Boulevard Birmingham, AL 35294-0099, USA.; Retina Consultants of Alabama P.C., 700 18th St S #707, Birmingham, AL 35233, USA., Crosson JN; Department of Ophthalmology and Visual Sciences, University of Alabama at Birmingham 1720 University Boulevard Birmingham, AL 35294-0099, USA.; Retina Consultants of Alabama P.C., 700 18th St S #707, Birmingham, AL 35233, USA.
Jazyk: angličtina
Zdroj: American journal of ophthalmology case reports [Am J Ophthalmol Case Rep] 2023 Mar; Vol. 29, pp. 101790. Date of Electronic Publication: 2022 Dec 29.
DOI: 10.1016/j.ajoc.2022.101790
Abstrakt: Purpose: To report a case of acute posterior multifocal placoid pigment epitheliopathy (APMPPE) following COVID-19 infection.
Observations: A 17-year-old female developed central scotomas and photopsias two weeks after SARS-CoV-2 diagnosis with polymerase chain reaction studies. She presented with poor visual acuity of 3/60 on the Feinbloom eye chart in the left eye. Dilated examination and multi-modal retinal imaging were consistent with the diagnosis of APMPPE, with noteworthy subretinal fluid. The patient was treated with an oral prednisone taper starting at 60mg with rapid resolution in subretinal fluid and improvement of visual acuity. Five weeks after presentation, visual acuity improved to 20/20 OU with complete resolution of the creamy white choroidal lesions and subretinal fluid.
Conclusion: There is a growing body of literature reporting the ocular manifestations of COVID-19. Rarely inflammation of the retina or choroid have been associated with the infection. To the best of our knowledge, there are no prior reports that describe the clinical course or visual outcome in a patient with APMPEE associated with recent COVID-19 infection. Accordingly, we are not aware of any other reports that describe the treatment of APMPEE associated with COVID-19 with corticosteroids. The mechanism linking COVID-19 infection to inflammatory ocular disorders in unclear and likely multi-factorial.
(© 2023 The Authors.)
Databáze: MEDLINE