Abdominal splenosis mimicking peritoneal carcinomatosis of ovarian cancer.

Autor: Alves FB; Department of Radiology, Centro Hospitalar Universitário de S. João, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal., Rombo DM; Department of Nuclear Medicine, Instituto Portugues de Oncologia de Lisboa Francisco Gentil, Rua Prof. Lima Basto, 1099-023 Lisboa, Portugal., Veiga V; Department of Ginecology, Instituto Portugues de Oncologia de Lisboa Francisco Gentil, Rua Prof. Lima Basto, 1099-023 Lisboa, Portugal., Correia PS; Department of Radiology, Centro Hospitalar e Universitário de Lisboa Central - Hospital de S. José, Rua José António Serrano, 1150-199 Lisboa, Portugal., Salgado L; Department of Nuclear Medicine, Instituto Portugues de Oncologia de Lisboa Francisco Gentil, Rua Prof. Lima Basto, 1099-023 Lisboa, Portugal., Cunha TM; Department of Radiology, Instituto Portugues de Oncologia de Lisboa Francisco Gentil, Rua Prof. Lima Basto, 1099-023 Lisboa, Portugal.
Jazyk: angličtina
Zdroj: Radiology case reports [Radiol Case Rep] 2022 Dec 26; Vol. 18 (3), pp. 932-935. Date of Electronic Publication: 2022 Dec 26 (Print Publication: 2023).
DOI: 10.1016/j.radcr.2022.11.071
Abstrakt: We present the clinical case of a 53-year-old woman referred for suspicion of recurrence of a mesonephric-like adenocarcinoma of the ovary. Abdominal and pelvic CT revealed multiple round/oval solid nodules with similar density scattered throughout the abdomen and pelvis, the biggest ones appearing in the left hypochondrium; no normal-appearing spleen or ascites were observed. These radiological findings and the absence of significant elevation of CA 125 levels made the radiologists hypothesize that these aspects were related to abdominal splenosis. They asked the patient about previous medical history of splenic injury, which she confirmed, referring it was a consequence of a remote major trauma. A  99m Tc-labeled heat-denatured erythrocytes ( 99m Tc-DRBC) scintigraphy/ hybrid SPECT/CT was then performed for definitive diagnosis; it showed spleen remnants as foci of increased radiopharmaceutical uptake in the same locations as the nodules appearing in the CT. This diagnostic work-up was consistent with abdominal splenosis, mimicking peritoneal carcinomatosis of ovarian cancer.
(© 2022 The Authors. Published by Elsevier Inc. on behalf of University of Washington.)
Databáze: MEDLINE