Age-, Sex-, and Race-Based Normal Values for Left Ventricular Circumferential Strain from the World Alliance Societies of Echocardiography Study.

Autor:	Singulane CC; University of Chicago, Chicago, Illinois., Miyoshi T; MedStar Health Research Institute, Washington, District of Columbia., Mor-Avi V; University of Chicago, Chicago, Illinois., Cotella JI; University of Chicago, Chicago, Illinois., Schreckenberg M; TomTec Imaging Systems, Unterschleissheim, Germany., Blankenhagen M; TomTec Imaging Systems, Unterschleissheim, Germany., Hitschrich N; TomTec Imaging Systems, Unterschleissheim, Germany., Addetia K; University of Chicago, Chicago, Illinois., Amuthan V; Jeyalakshmi Heart Center, Madurai, India., Citro R; University of Salerno, Salerno, Italy., Daimon M; University of Tokyo, Tokyo, Japan., Gutiérrez-Fajardo P; Hospitales Mac Bernardette, Guadalajara, Mexico., Kasliwal R; Medanta Heart Institute, Gurgaon, India., Kirkpatrick JN; University of Washington, Seattle, Washington., Monaghan MJ; King's College Hospital, London, United Kingdom., Muraru D; Istituto Auxologico Italiano, IRCCS, San Luca Hospital, and University of Milano-Bicocca, Milan, Italy., Ogunyankin KO; First Cardiology Consultants Hospital, Lagos, Nigeria., Park SW; Samsung Medical Center, Seoul, Korea., Tude Rodrigues AC; Albert Einstein Hospital, Sao Paulo, Brazil., Ronderos R; Instituto Cardiovascular de Buenos Aires, Buenos Aires, Argentina., Sadeghpour A; Rajaie Cardiovascular Medical and Research Center, Echocardiography Research Center, IUMS, Tehran, Iran., Scalia GM; Genesis Care, Brisbane, Australia., Takeuchi M; University of Occupational and Environmental Health, Kitakyushu, Japan., Tsang W; Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada., Tucay ES; Philippine Heart Center, Quezon City, Philippines., Zhang Y; Qilu Hospital of Shandong University, Jinan, China., Asch FM; MedStar Health Research Institute, Washington, District of Columbia., Lang RM; University of Chicago, Chicago, Illinois. Electronic address: rlang@medicine.bsd.uchicago.edu.
Jazyk:	angličtina
Zdroj:	Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography [J Am Soc Echocardiogr] 2023 Jun; Vol. 36 (6), pp. 581-590.e1. Date of Electronic Publication: 2022 Dec 30.
DOI:	10.1016/j.echo.2022.12.018
Abstrakt:	Background: Left ventricular (LV) circumferential strain has received less attention than longitudinal deformation, which has recently become part of routine clinical practice. Among other reasons, this is because of the lack of established normal values. Accordingly, the aim of this study was to establish normative values for LV circumferential strain and determine sex-, age-, and race-related differences in a large cohort of healthy adults. Methods: Complete two-dimensional transthoracic echocardiograms were obtained in 1,572 healthy subjects (51% men), enrolled in the World Alliance Societies of Echocardiography Normal Values Study. Subjects were divided into three age groups (<35, 35-55, and >55 years) and stratified by sex and by race. Vendor-independent semiautomated speckle-tracking software was used to determine LV regional circumferential strain and global circumferential strain (GCS) values. Limits of normal for each measurement were defined as 95% of the corresponding sex and age group falling between the 2.5th and 97.5th percentiles. Intergroup differences were analyzed using unpaired t tests. Results: Circumferential strain showed a gradient, with lower magnitude at the mitral valve level, increasing progressively toward the apex. Compared with men, women had statistically higher magnitudes of regional and global strain. Older age was associated with a stepwise increase in GCS despite an unaffected ejection fraction, a decrease in LV volume, and relatively stable global longitudinal strain in men, with a small gradual decrease in women. Asian subjects demonstrated significantly higher GCS magnitudes than whites of both sexes and blacks among women only. In contrast, no significant differences in GCS were found between white and black subjects of either sex. Importantly, despite statistical significance of these differences across sex, age, and race, circumferential strain values were similar in all groups, with variations of the order of magnitude of 1% to 2%. Notably, no differences in GCS were found among brands of imaging equipment. Conclusion: This study established normal values of LV regional circumferential strain and GCS and identified sex-, age-, and race-related differences when present. (Copyright © 2022 American Society of Echocardiography. Published by Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu