Herpes Simplex Encephalitis: Detection, Management, and Outcomes.

Autor:	Rayan MN; Internal Medicine, University of Central Florida College of Medicine, Graduate Medical Education/North Florida Regional Medical Center, Gainesville, USA., Bassi R; Internal Medicine, University of Central Florida College of Medicine, Graduate Medical Education/North Florida Regional Medical Center, Gainesville, USA., Khazem M; Radiology, University of Florida Shands, Gainesville, USA.; Internal Medicine, University of Central Florida College of Medicine, Graduate Medical Education/HCA Florida North Florida Hospital, Gainesville, USA., Pozo DA; Internal Medicine, University of Central Florida College of Medicine, Graduate Medical Education/North Florida Regional Medical Center, Gainesville, USA., Abduljaber W; Internal Medicine, University of Central Florida College of Medicine, Graduate Medical Education/North Florida Regional Medical Center, Gainesville, USA., Burtis DB; Neurology, HCA Florida North Florida Hospital, Gainesville, USA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2022 Nov 28; Vol. 14 (11), pp. e31962. Date of Electronic Publication: 2022 Nov 28 (Print Publication: 2022).
DOI:	10.7759/cureus.31962
Abstrakt:	The pathophysiology of herpes simplex encephalitis (HSE) is incompletely understood and proposed to be secondary to the retrograde transport of the herpes simplex virus type 1 (HSV-1) via the trigeminal and/or olfactory nerves to the central nervous system (CNS). In this case report, we present a 68-year-old female who presents to our emergency department after a fall. Upon initial admission, her neurological examination was benign, and a computer tomography (CT) scan of her brain showed a subdural hematoma for which she was treated conservatively. Day 4 of her hospitalization marked a rapid decline in her course of illness, beginning with confusion and hallucinations, progressing to subclinical seizures, and culminating in irreversible brain damage and palliative extubation on day 16 of hospitalization. This case report discusses our insight into the challenges of early diagnosis and treatment of herpes encephalitis and their impact on improving patient outcomes. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2022, Rayan et al.)
Databáze:	MEDLINE
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