Introduction and Clinical Validation of an Updated Biomechanically Corrected Intraocular Pressure bIOP (v2).

Autor: Eliasy A; School of Engineering, University of Liverpool, Liverpool, UK., Lopes BT; School of Engineering, University of Liverpool, Liverpool, UK.; Department of Ophthalmology, Federal University of São Paulo (UNIFESP), São Paulo, Brazil., Wang J; Eye Hospital, Wenzhou Medical University, Wenzhou, China., Abass A; School of Engineering, University of Liverpool, Liverpool, UK.; Department of Production Engineering and Mechanical Design, Faculty of Engineering, Port Said University, Egypt., Vinciguerra R; School of Engineering, University of Liverpool, Liverpool, UK.; Department of Opthalmology, Humanitas San Pio X Hospital, Milan, Italy., Vinciguerra P; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Humanitas Clinical and Research Center, IRCCS, Rozzano, Italy., Bao FJ; Eye Hospital, Wenzhou Medical University, Wenzhou, China., Elsheikh A; School of Engineering, University of Liverpool, Liverpool, UK.; Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China.; NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, UK.
Jazyk: angličtina
Zdroj: Current eye research [Curr Eye Res] 2023 Apr; Vol. 48 (4), pp. 382-391. Date of Electronic Publication: 2022 Dec 29.
DOI: 10.1080/02713683.2022.2162087
Abstrakt: Purpose: To improve the stability of the Corvis ST biomechanically-corrected intraocular pressure measurements (bIOP) after refractive surgery and its independence of corneal biomechanics.
Methods: A parametric study was carried out using numerical models simulating the behavior of the eye globe under the effects of IOP and Corvis ST external air pressure and used to develop a new algorithm for bIOP; bIOP(v2). It was tested on 528 healthy participants to evaluate correlations with CCT and age. Its ability to compensate for the geometrical changes was tested in 60 LASIK and 80 SMILE patients with six months follow up. The uncorrected Corvis ST IOP (CVS-IOP) and the two versions of biomechanically corrected IOP; bIOP(v1) and bIOP(v2), were compared.
Results: In the healthy dataset, bIOP(v2) had weak and non-significant correlation with both CCT (R = -0.048, p  = .266) and age (R = 0.085, p  = .052). For bIOP(v1), the correlation was non-significant with CCT (R = -0.064, p  = .139) but significant with age (R = -0.124, p  < .05). In both LASIK and SMILE groups, the median change in bIOP(v2) following surgery was below 1 mmHg at follow-up stages and the interquartile range was smaller than both bIOP(v1) and CVS-IOP.
Conclusion: The bIOP(v2) algorithm performs better than bIOP(v1) and CVS-IOP in terms of correlation with CCT and age. The bIOP(v2) also demonstrated the smallest variation after LASIK and SMILE refractive surgeries indicating improved ability to compensate for geometrical changes.
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje