Hypertensive pneumothorax with cystic lesions: Pleuropulmonary blastoma in an infant.

Autor:	Lamberti R; Pediatric Department, 'Vittore Buzzi' Children's Hospital, 20154, Milan, Italy., Ghezzi M; Pediatric Department, 'Vittore Buzzi' Children's Hospital, 20154, Milan, Italy., Riccaboni F; Pediatric Department, 'Vittore Buzzi' Children's Hospital, 20154, Milan, Italy., Farolfi A; Pediatric Department, 'Vittore Buzzi' Children's Hospital, 20154, Milan, Italy., Zirpoli S; Radiology Department, 'Vittore Buzzi' Children's Hospital, 20154, Milan, Italy., Zenga A; Pediatric Department, 'Vittore Buzzi' Children's Hospital, 20154, Milan, Italy., Riccipetitoni G; Pediatric Surgery Unit, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy., Zuccotti G; Pediatric Department, 'Vittore Buzzi' Children's Hospital, 20154, Milan, Italy.; Department of Biomedical and Clinical Science 'L. Sacco', University of Milan, 20157, Milan, Italy., D'Auria E; Pediatric Department, 'Vittore Buzzi' Children's Hospital, 20154, Milan, Italy.
Jazyk:	angličtina
Zdroj:	Respiratory medicine case reports [Respir Med Case Rep] 2022 Dec 13; Vol. 41, pp. 101793. Date of Electronic Publication: 2022 Dec 13 (Print Publication: 2023).
DOI:	10.1016/j.rmcr.2022.101793
Abstrakt:	Pleuropulmonary blastoma (PPB) is a rare primitive malignant lung cancer that occurs in pediatric age. Its main differential diagnosis is congenital cystic pulmonary malformation (CPAM). A 30-day-old infant with respiratory failure obtained a chest x-ray and a computed tomography scan (CT) which revealed hypertensive pneumothorax with multifocal bilateral cysts. After thoracic drainage, the patient underwent multiple thoracoscopic pulmonary resections. The first histological diagnosis was of type 2 CPAM. During the radiological follow-up, an increase in the number and dimension of the lesions was detected. Thus, a histological revision was performed, leading to the diagnosis of type I PPB, at nine months. The patient subsequently underwent chemotherapy. At the five-year follow-up appointment, chest magnetic resonance (MR) and CT scans showed a dimensional increase in size of the lesions, with the risk of recurrent pneumothorax. An upper right lobectomy and wedge resection of the residual cysts were performed. Control MR scans showed normalization of the lung parenchyma and the patient showed substantial clinical improvement. Competing Interests: There are no conflicts of interest to declare. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. (© 2022 Published by Elsevier Ltd.)
Databáze:	MEDLINE
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