Do preoperative leukocyte and neutrophil levels have a predictive value on the complications of hypospadias repair in children?

Autor: Karagözlü Akgül A; Marmara University Faculty of Medicine, Department of Pediatric Surgery, Division of Pediatric Urology, Istanbul. ahsenkaragozlu@yahoo.com., Abidoğlu S; Marmara University Faculty of Medicine, Department of Pediatric Surgery, Division of Pediatric Urology, Istanbul. s_abidoglu@yahoo.com., Bakır AC; Ministry of Health, Marmara University Pendik Education and Research Hospital, Department of Pediatric Surgery, Istanbul. aytenceren@gmail.com., Adalı E; St. Helens and Knowsley Teaching Hospitals, Department of Pediatric Accident and Emergency Medicine. embiye.mba@gmail.com., Kıyan G; Marmara University Faculty of Medicine, Department of Pediatric Surgery, Istanbul. gursukiyan@gmail.com., Tuğtepe H; Tug˘tepe Center of Pediatric Urology and Pediatric Surgery, Istanbul. htugtepe@yahoo.com.
Jazyk: angličtina
Zdroj: Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica [Arch Ital Urol Androl] 2022 Dec 27; Vol. 94 (4), pp. 459-463. Date of Electronic Publication: 2022 Dec 27.
DOI: 10.4081/aiua.2022.4.459
Abstrakt: Objective: Surgeons observed that the outcomes after the same repair technique in the same type of hypospadias performed by the same surgeon may be different. There may be some indeterminate factors that influence the results such as subclinical inflammation. Our study evaluated the predictor values of inflammatory hematologic parameters on the complications after hypospadias repair.
Materials and Methods: We retrospectively reviewed the data of patients who underwent hypospadias repair between January 2016 and January 2019 in our clinic. Age at surgery, hypospadias type, repair technique, complications were recorded. Patients who underwent Snodgrass repair by a single surgeon were included in the study while patients who underwent different techniques or procedures that were performed by other surgeons were excluded. The levels of white blood cell, neutrophil, lymphocyte, platelet and monocyte, the mean platelet volumes were recorded from blood test that were performed one day before surgery. Neutrophil-lymphocyte ratio (NLR), plateletlymphocyte ratio (PLR), and other parameters were analyzed to determine their relationship with complications after hypospadias surgery.
Results: WBC and neutrophil levels were statistically higher in patients with complications (p = 0.006 and 0.017 respectively). Other hematological parameters were not different between patients with or without complications. To predict the complications, the WBC cutoff was 9500/mm3, the neutrophil cutoff was 3000/mm3.
Conclusions: WBC and neutrophil values were statistically significant in predicting the complications after Snodgrass repair in patients with hypospadias. Our result determined no relation between complications and NLR, PLR.
Databáze: MEDLINE
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