Skin manifestations following anti-COVID-19 vaccination: A multicentricstudy from Turkey.

Autor: Oguz Topal I; Department of Dermatology and Venereology, University of Health Sciences, Prof. Dr. Cemil Tascioglu City Hospital, Istanbul, Turkey., Tokmak A; Department of Dermatology and Venereology, Agri Training and Research Hospital, Agri, Turkey., Kurmuş GI; Department of Dermatology and Venereology, Faculty of Medicine, Yüksek İhtisas University, Ankara, Turkey., Kalkan G; Department of Dermatology and Venereology, Yildirim Beyazit University, Medical School, Ankara, Turkey., Demirseren DD; Department of Dermatology and Venereology, University of Health Sciences, Ankara City Hospital, Ankara, Turkey., Tosun M; Department of Dermatology and Venereology, Sivas Cumhuriyet University, Sivas, Turkey., Emre S; Department of Dermatology and Venereology, Yildirim Beyazit University, Medical School, Ankara, Turkey., Özkök Akbulut T; Department of Dermatology and Venereology, University of Health Sciences, Haseki Training and Research Hospital, Istanbul, Turkey., Kaya Özden H; Department of Dermatology and Venereology, Kocaeli Derince Training and Research Hospital, Kocaeli, Turkey., Koska MC; Department of Dermatology and Venereology, Artvin State Hospital, Artvin, Turkey., Külcü Çakmak S; Department of Dermatology and Venereology, University of Health Sciences, Ankara City Hospital, Ankara, Turkey., Kutlu Ö; Department of Dermatology and Venereology, Gaziosmanpaşa University Medical Faculty, Tokat, Turkey., Mutlu E; Department of Dermatology and Venereology, Cankiri State Hospital, Cankiri, Turkey., Gür Aksoy G; Department of Dermatology and Venereology, University of Health Sciences, Ankara City Hospital, Ankara, Turkey., Topaloğlu Demir F; Department of Dermatology and Venereology, Faculty of Medicine, Istanbul Medipol University, Istanbul, Turkey., Karadağ AS; Department of Dermatology and Venereology, Memorial Ataşehir Hospital, Istanbul, Turkey.
Jazyk: angličtina
Zdroj: Journal of cosmetic dermatology [J Cosmet Dermatol] 2023 Feb; Vol. 22 (2), pp. 354-363. Date of Electronic Publication: 2022 Dec 27.
DOI: 10.1111/jocd.15570
Abstrakt: Purpose: After the emergence of the pandemic caused by the COVID-19 virus, vaccination with various vaccines has started to be implemented across the world. To identify dermatological reactions developing after the COVID-19 vaccines administered in Turkey and determine their clinical features and risk factors that may play a role in their development.
Materials and Methods: The study included patients aged ≥18 years, who presented to 13 different dermatology clinics in Turkey between July 2021 and September 2021 after developing dermatological reactions following the administration of the COVID-19 vaccine. After providing written consent, the patients were asked to complete a standard survey including questions related to age, gender, occupation, comorbidities, the regular medication used, the onset of cutaneous reactions after vaccination, and localization of reactions. Dermatological reactions were categorized according to whether they developed after the first or second dose of the vaccine or whether they occurred after the inactivated or messenger RNA (mRNA) vaccine. The relationship between dermatological reactions and some variables such as gender and comorbidities was also evaluated.
Results: A total of 269 patients [116 women (43.1%), 153 men (56.9%)] were included in the study. It was observed that the dermatological diseases and reactions that most frequently developed after vaccination were urticaria (25.7%), herpes zoster (24.9%), maculopapular eruption (12.3%), and pityriasis rosea (4.5%). The rate of dermatological reactions was 60.6% after the administration of the mRNA vaccine and 39.4% after that of the inactivated vaccine. There was a statistically significantly higher number of reactions among the patients that received the mRNA vaccine (p = 0.001).
Conclusion: The most common reactions in our sample were urticaria, herpes zoster, and maculopapular eruption. Physicians should know the dermatological side effects of COVID-19 vaccines and their clinical features.
(© 2022 The Authors. Journal of Cosmetic Dermatology published by Wiley Periodicals LLC.)
Databáze: MEDLINE
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