Photochemical Optimization of a Silver Nanoprism/Graphene Oxide Nanocomposite's Antibacterial Properties.

Autor:	Benalcázar J; Yachay Tech University, School of Physical Sciences and Nanotechnology, 100119Urcuquí, Ecuador., Lasso ED; Yachay Tech University, School of Physical Sciences and Nanotechnology, 100119Urcuquí, Ecuador., Ibarra-Barreno CM; Yachay Tech University, School of Physical Sciences and Nanotechnology, 100119Urcuquí, Ecuador., Arcos Pareja JA; Yachay Tech University, School of Physical Sciences and Nanotechnology, 100119Urcuquí, Ecuador., Vispo NS; Yachay Tech University, School of Biological Sciences and Engineering, 100119Urcuquí, Ecuador., Chacón-Torres JC; Yachay Tech University, School of Physical Sciences and Nanotechnology, 100119Urcuquí, Ecuador., Briceño S; Yachay Tech University, School of Physical Sciences and Nanotechnology, 100119Urcuquí, Ecuador.
Jazyk:	angličtina
Zdroj:	ACS omega [ACS Omega] 2022 Dec 09; Vol. 7 (50), pp. 46745-46755. Date of Electronic Publication: 2022 Dec 09 (Print Publication: 2022).
DOI:	10.1021/acsomega.2c05793
Abstrakt:	Optimizing the antibacterial properties of nanocomposites is a fundamental challenge for many biomedical applications. Here, we study how we may optimize the antibacterial activity of narrow-sized anisotropically flat silver nanoprisms (S-NPs) on graphene oxide (GO) against Escherichia coli . To do so, we transformed silver nanoparticles (AgNPs) into S-NPs and anchored them to GO via a facile and low-cost photochemical reduction method by varying the irradiation wavelength during the synthesis process in the visible range (440 to 650 nm and white light). We performed a physicochemical characterization of the resulting S-NP/GO nanocomposite using a combination of UV-vis spectroscopy, X-ray photoelectron spectroscopy (XPS), Raman spectroscopy, scanning electron microscopy (SEM), and transmission electron microscopy (TEM). Our results reveal a synergistic effect between the silver nanoprism and the oxygen functional groups of the GO surface. The antibacterial activity of the S-NPs/GO nanocomposite shows a significantly higher 53% inhibition efficiency after being irradiated with a 540 nm wavelength light source, compared to AgNPs with a 1% inhibition efficiency, respectively. In so doing, we have demonstrated the utility of a low-cost photoreduction method to control the structural properties of silver nanoprism on GO and, in this way, enhance the antibacterial properties of the nanocomposite. These results should be of great interest in a wide range of biomedical applications and medical devices. Competing Interests: The authors declare no competing financial interest. (© 2022 The Authors. Published by American Chemical Society.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu