Dataset linking free polyunsaturated fatty acid concentrations in erythrocytes with chronic pain conditions in adults.

Autor:	Soma PS; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States., Ehrmann BM; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States., Slade GD; Division of Pediatric and Public Health, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Sanders AE; Division of Pediatric and Public Health, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Weatherspoon ED; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States.
Jazyk:	angličtina
Zdroj:	Data in brief [Data Brief] 2022 Dec 05; Vol. 46, pp. 108802. Date of Electronic Publication: 2022 Dec 05 (Print Publication: 2023).
DOI:	10.1016/j.dib.2022.108802
Abstrakt:	Circulating polyunsaturated fatty acids (PUFAs) and lipid mediators were extracted from human red blood cells and quantified using liquid chromatography-tandem mass spectrometry (LC-MS/MS). The method encompassed 13 different PUFAs and lipid mediators, however, due to instrument capability only five were confidently quantified (EPA, ALA, AA, DHA, and LA). The extraction focused on free polyunsaturated fatty acids since they have a strong correlation with health in humans. The study design was a secondary analysis of the OPPERA-2 study of chronic overlapping pain conditions in adults. The data included are: a) raw LC-MS/MS data (.raw); b) processed data (.xlsx) including chromatographic peak area for each compound and a concentration (ng/mL) based on external calibration with internal standardization using pure analytical grade standards and heavy-isotope labeled internal standards; c) study participant demographics and phenotypes (.xlsx). This dataset consisting of circulating PUFA quantities measured in 605 humans has been made publicly available for analysis and interpretation. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu