Emergence of High Pathogenicity Avian Influenza Virus H5N1 Clade 2.3.4.4b in Wild Birds and Poultry in Botswana.

Autor: Letsholo SL; Botswana National Veterinary Laboratory (BNVL), Private Bag 0035, Gaborone, Botswana., James J; Animal and Plant Health Agency (APHA)-Woodham Ln, Addlestone KT15 3NB, UK., Meyer SM; Animal and Plant Health Agency (APHA)-Woodham Ln, Addlestone KT15 3NB, UK., Byrne AMP; Animal and Plant Health Agency (APHA)-Woodham Ln, Addlestone KT15 3NB, UK., Reid SM; Animal and Plant Health Agency (APHA)-Woodham Ln, Addlestone KT15 3NB, UK., Settypalli TBK; Animal Production and Health Laboratory (APHL), United Nations Food and Agriculture Organisation (FAO)/International Atomic Energy Agency (IAEA) Agriculture and Biotechnology Laboratory, IAEA Laboratories, Friedenstrasse 1, 2444 Seibersdorf, Austria., Datta S; Animal Production and Health Laboratory (APHL), United Nations Food and Agriculture Organisation (FAO)/International Atomic Energy Agency (IAEA) Agriculture and Biotechnology Laboratory, IAEA Laboratories, Friedenstrasse 1, 2444 Seibersdorf, Austria., Oarabile L; Department of Veterinary Services (DVS), Ministry of Agriculture, Private Bag 0032, Gaborone, Botswana., Kemolatlhe O; Department of Veterinary Services (DVS), Ministry of Agriculture, Private Bag 0032, Gaborone, Botswana., Pebe KT; Department of Veterinary Services (DVS), Ministry of Agriculture, Private Bag 0032, Gaborone, Botswana., Mafonko BR; Department of Veterinary Services (DVS), Ministry of Agriculture, Private Bag 0032, Gaborone, Botswana., Kgotlele TJ; Botswana National Veterinary Laboratory (BNVL), Private Bag 0035, Gaborone, Botswana., Kumile K; Botswana National Veterinary Laboratory (BNVL), Private Bag 0035, Gaborone, Botswana., Modise B; Botswana National Veterinary Laboratory (BNVL), Private Bag 0035, Gaborone, Botswana., Thanda C; Botswana National Veterinary Laboratory (BNVL), Private Bag 0035, Gaborone, Botswana., Nyange JFC; Botswana National Veterinary Laboratory (BNVL), Private Bag 0035, Gaborone, Botswana., Marobela-Raborokgwe C; Botswana National Veterinary Laboratory (BNVL), Private Bag 0035, Gaborone, Botswana., Cattoli G; Animal Production and Health Laboratory (APHL), United Nations Food and Agriculture Organisation (FAO)/International Atomic Energy Agency (IAEA) Agriculture and Biotechnology Laboratory, IAEA Laboratories, Friedenstrasse 1, 2444 Seibersdorf, Austria., Lamien CE; Animal Production and Health Laboratory (APHL), United Nations Food and Agriculture Organisation (FAO)/International Atomic Energy Agency (IAEA) Agriculture and Biotechnology Laboratory, IAEA Laboratories, Friedenstrasse 1, 2444 Seibersdorf, Austria., Brown IH; Animal and Plant Health Agency (APHA)-Woodham Ln, Addlestone KT15 3NB, UK., Dundon WG; Animal Production and Health Laboratory (APHL), United Nations Food and Agriculture Organisation (FAO)/International Atomic Energy Agency (IAEA) Agriculture and Biotechnology Laboratory, IAEA Laboratories, Friedenstrasse 1, 2444 Seibersdorf, Austria., Banyard AC; Animal and Plant Health Agency (APHA)-Woodham Ln, Addlestone KT15 3NB, UK.
Jazyk: angličtina
Zdroj: Viruses [Viruses] 2022 Nov 22; Vol. 14 (12). Date of Electronic Publication: 2022 Nov 22.
DOI: 10.3390/v14122601
Abstrakt: Numerous outbreaks of high-pathogenicity avian influenza (HPAI) were reported during 2020-2021. In Africa, H5Nx has been detected in Benin, Burkina Faso, Nigeria, Senegal, Lesotho, Namibia and South Africa in both wild birds and poultry. Botswana reported its first outbreak of HPAI to the World Organisation for Animal Health (WOAH) in 2021. An H5N1 virus was detected in a fish eagle, doves, and chickens. Full genome sequence analysis revealed that the virus belonged to clade 2.3.4.4b and showed high identity within haemagglutinin (HA) and neuraminidase proteins (NA) for viruses identified across a geographically broad range of locations. The detection of H5N1 in Botswana has important implications for disease management, wild bird conservation, tourism, public health, economic empowerment of vulnerable communities and food security in the region.
Databáze: MEDLINE
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