Kombuchas from Green and Black Tea Modulate the Gut Microbiota and Improve the Intestinal Health of Wistar Rats Fed a High-Fat High-Fructose Diet.

Autor:	Costa MAC; Department of Food Technology, Universidade Federal de Viçosa, Avenida Peter Henry Rolfs, s/n, Viçosa 36570-900, MG, Brazil., Dias Moreira LP; Department of Agronomy, Food Natural Resources, Animals, and Environment (DAFNAE), Università degli Studi di Padova, Via dell'Università 16, 35020 Legnaro, PD, Italy., Duarte VDS; Faculty of Chemistry, Biotechnology, and Food Science, The Norwegian University of Life Sciences, P.O. Box 5003, 1432 Ås, Norway., Cardoso RR; Department of Food Technology, Universidade Federal de Viçosa, Avenida Peter Henry Rolfs, s/n, Viçosa 36570-900, MG, Brazil., São José VPB; Department of Nutrition and Health, Universidade Federal de Viçosa, Avenida Peter Henry Rolfs, s/n, Viçosa 36570-000, MG, Brazil., Silva BPD; Department of Nutrition and Health, Universidade Federal de Viçosa, Avenida Peter Henry Rolfs, s/n, Viçosa 36570-000, MG, Brazil., Grancieri M; Department of Nutrition and Health, Universidade Federal de Viçosa, Avenida Peter Henry Rolfs, s/n, Viçosa 36570-000, MG, Brazil., Corich V; Department of Agronomy, Food Natural Resources, Animals, and Environment (DAFNAE), Università degli Studi di Padova, Via dell'Università 16, 35020 Legnaro, PD, Italy., Giacomini A; Department of Agronomy, Food Natural Resources, Animals, and Environment (DAFNAE), Università degli Studi di Padova, Via dell'Università 16, 35020 Legnaro, PD, Italy., Bressan J; Department of Nutrition and Health, Universidade Federal de Viçosa, Avenida Peter Henry Rolfs, s/n, Viçosa 36570-000, MG, Brazil., Martino HSD; Department of Nutrition and Health, Universidade Federal de Viçosa, Avenida Peter Henry Rolfs, s/n, Viçosa 36570-000, MG, Brazil., Barros FAR; Department of Food Technology, Universidade Federal de Viçosa, Avenida Peter Henry Rolfs, s/n, Viçosa 36570-900, MG, Brazil.
Jazyk:	angličtina
Zdroj:	Nutrients [Nutrients] 2022 Dec 08; Vol. 14 (24). Date of Electronic Publication: 2022 Dec 08.
DOI:	10.3390/nu14245234
Abstrakt:	The Western diet can negatively affect the gut microbiota and is associated with metabolic disorders. Kombucha, a tea fermented by a symbiotic culture of bacteria and yeast (SCOBY), is known for its bioactive properties and has become popular in the last years. In this study, we evaluated the effects of regular kombucha consumption on the gut microbiota and on outcomes related to the intestinal health of Wistar rats fed a high-fat high-fructose diet. After eight weeks receiving a standard diet (AIN-93M) (n = 10) or a high-fat and high-fructose diet (HFHF) (n = 30) to induce metabolic disorders, the animals were subdivided into four groups: AIN-93M (n = 10); HFHF (n = 10); GTK (HFHF + green tea kombucha (n = 10); and BTK (HFHF + black tea kombucha; n = 10) for 10 weeks. Although body composition did not differ among the groups, the HFHF diet was associated with metabolic alterations, and stimulated the growth of gram-negative bacteria such as Proteobacteria and Bacteroides . Kombucha ingestion could somewhat modulate the gut microbiota, attenuating the effects of a Western diet by increasing propionate production and favoring the growth of beneficial bacteria, such as Adlercreutzia in the GTK group. Our results suggest that regular kombucha consumption may be beneficial to intestinal health, which can be mostly attributed to its high content and diversity of phenolic compounds.
Databáze:	MEDLINE
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