Pathogen Detection in Ornithodoros sonrai Ticks and Invasive House Mice Mus musculus domesticus in Senegal.

Autor: Ouarti B; Aix-Marseille University, IRD, SSA, AP-HM, VITROME, 13005 Marseille, France.; IHU-Méditerranée Infection, 13005 Marseille, France., Sall M; UFR des Sciences Appliquées et de Technologie, Section Informatique, University Gaston Berger, Saint-Louis 32000, Senegal., Ndiaye EHI; Aix-Marseille University, IRD, SSA, AP-HM, VITROME, 13005 Marseille, France.; IHU-Méditerranée Infection, 13005 Marseille, France.; Institut de Recherche Pour le Développement (IRD), VITROME IRD 257, Campus International IRD-UCAD, Hann, Dakar 1386, Senegal., Diatta G; Institut de Recherche Pour le Développement (IRD), VITROME IRD 257, Campus International IRD-UCAD, Hann, Dakar 1386, Senegal., Zan Diarra A; Aix-Marseille University, IRD, SSA, AP-HM, VITROME, 13005 Marseille, France.; IHU-Méditerranée Infection, 13005 Marseille, France., Berenger JM; Aix-Marseille University, IRD, SSA, AP-HM, VITROME, 13005 Marseille, France.; IHU-Méditerranée Infection, 13005 Marseille, France., Sokhna C; Aix-Marseille University, IRD, SSA, AP-HM, VITROME, 13005 Marseille, France.; IHU-Méditerranée Infection, 13005 Marseille, France.; Institut de Recherche Pour le Développement (IRD), VITROME IRD 257, Campus International IRD-UCAD, Hann, Dakar 1386, Senegal., Granjon L; Centre de Biologie Pour la Gestion des Populations, Institut de Recherche Pour Développement, Centre de Coopération Internationale en Recherche Agronomique Pour le Développement, Institut National de Recherche Pour l'Agriculture, l'Alimentation et l'Environnement, Institut Agro Montpellier, University Montpellier, Lez CEDEX, 34988 Montferrier, France., Le Fur J; Centre de Biologie Pour la Gestion des Populations, Institut de Recherche Pour Développement, Centre de Coopération Internationale en Recherche Agronomique Pour le Développement, Institut National de Recherche Pour l'Agriculture, l'Alimentation et l'Environnement, Institut Agro Montpellier, University Montpellier, Lez CEDEX, 34988 Montferrier, France., Parola P; Aix-Marseille University, IRD, SSA, AP-HM, VITROME, 13005 Marseille, France.; IHU-Méditerranée Infection, 13005 Marseille, France.
Jazyk: angličtina
Zdroj: Microorganisms [Microorganisms] 2022 Nov 30; Vol. 10 (12). Date of Electronic Publication: 2022 Nov 30.
DOI: 10.3390/microorganisms10122367
Abstrakt: Ornithodoros sonrai ( O. sonrai ) ticks are the only known vectors of Borrelia crocidurae , an agent of tick-borne relapsing fever (TBRF) borreliosis. Rodents serve as principal natural reservoirs for Borrelia . Our research objective was to detect TBRF Borrelia and other zoonotic bacterial infections in ticks and in house mice Mus musculus domesticus , an invasive species currently expanding in rural northern Senegal. Real-time and conventional PCR were utilized for detecting Borrelia and other bacterial taxa. The analyses were performed on 253 specimens of O . sonrai and 150 samples of brain and spleen tissue from rodents. Borrelia crocidurae was found in one O. sonrai tick and 18 Mus musculus domesticus samples, with prevalences of 0.39 percent and 12 percent, respectively, as well as Ehrlichia sp. in one Mus musculus domesticus . Further, we were able to detect the presence of a potentially infectious novel species belonging to the Anaplasmataceae family for the first time in O. sonrai ticks. More attention should be paid to the house mouse and O. sonrai ticks, as they can be potential hosts for novel species of pathogenic bacteria in humans.
Databáze: MEDLINE
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