Transition to Fast Whole-Body SPECT/CT Bone Imaging: An Assessment of Image Quality.

Autor: Alqahtani M; Discipline of Medical Imaging Science, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW 2006, Australia.; Department of Radiology and Medical Imaging, Faculty of Applied Medical Sciences, Najran University, Najran 61441, Saudi Arabia., Willowson K; Department of Nuclear Medicine, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.; Institute of Medical Physics, Faculty of Science, The University of Sydney, Sydney, NSW 2006, Australia., Fulton R; Discipline of Medical Imaging Science, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW 2006, Australia.; Department of Medical Physics, Westmead Hospital, Sydney, NSW 2145, Australia., Constable C; HERMES Medical Solutions, Strandbergsgatan 16, 112 51 Stockholm, Sweden., Kench P; Discipline of Medical Imaging Science, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW 2006, Australia.
Jazyk: angličtina
Zdroj: Diagnostics (Basel, Switzerland) [Diagnostics (Basel)] 2022 Nov 24; Vol. 12 (12). Date of Electronic Publication: 2022 Nov 24.
DOI: 10.3390/diagnostics12122938
Abstrakt: Objective: To investigate the impact of reduced SPECT acquisition time on reconstructed image quality for diagnostic purposes.
Method: Data from five patients referred for a routine bone SPECT/CT using the standard multi-bed SPECT/CT protocol were reviewed. The acquisition time was 900 s using gating technique; SPECT date was resampled into reduced data sets of 480 s, 450 s, 360 s and 180 s acquisition duration per bed position. Each acquisition time was reconstructed using a fixed number of subsets (8 subsets) and 4, 8, 12, and 16 iterations, followed by a post-reconstruction 3D Gaussian filter of 8 mm FWHM. Two Nuclear Medicine physicians analysed all images independently to score image quality, noise and diagnostic confidence based on a pre-defined 4-point scale.
Results: Our result showed that the most frequently selected categories for 480 s and 450 s images were good image quality, average noise and fair confidence, particularly at lower iteration numbers 4 and 8. For the shortened acquisition time of 360 s and 180 s, statistical significance was observed in most reconstructed images compared with 900 s.
Conclusion: The SPECT/CT can significantly shorten the acquisition time with maintained image quality, noise and diagnostic confidence. Therefore, acquiring data over 480 s and 450 s is feasible for WB-SPECT/CT bone scans to provide an optimal balance between acquisition time and image quality.
Competing Interests: The authors declare no conflict of interest.
Databáze: MEDLINE
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