Uterine Artery Embolisation of Fibroids and the Phenomenon of Post-Embolisation Syndrome: A Systematic Review.

Autor: Waldron MG; Department of Radiology, University College Cork, T12 AK54 Cork, Ireland., Kassamani YW; School of Medicine, University College Cork, T12 AK54 Cork, Ireland., O'Mahony AT; Department of Radiology, Cork University Hospital, T12 DFK4 Cork, Ireland., O'Mahony SM; Department of Anatomy, University College Cork, T12 XF62 Cork, Ireland., O'Sullivan OE; Department of Obstetrics and Gynaecology, Cork University Hospital, T12 DFK4 Cork, Ireland., Power SP; Department of Radiology, Cork University Hospital, T12 DFK4 Cork, Ireland., Spence L; Department of Radiology, Cork University Hospital, T12 DFK4 Cork, Ireland., Maher MM; Department of Radiology, University College Cork, T12 AK54 Cork, Ireland.; Department of Radiology, Cork University Hospital, T12 DFK4 Cork, Ireland.; Department of Obstetrics and Gynaecology, Cork University Hospital, T12 DFK4 Cork, Ireland., O'Connor OJ; Department of Radiology, University College Cork, T12 AK54 Cork, Ireland.; Department of Radiology, Cork University Hospital, T12 DFK4 Cork, Ireland., Buckley MM; APC Microbiome Ireland, University College Cork, T12 TP07 Cork, Ireland.; Department of Pharmacology and Therapeutics, University College Cork, T12 XF62 Cork, Ireland.
Jazyk: angličtina
Zdroj: Diagnostics (Basel, Switzerland) [Diagnostics (Basel)] 2022 Nov 23; Vol. 12 (12). Date of Electronic Publication: 2022 Nov 23.
DOI: 10.3390/diagnostics12122916
Abstrakt: Post-embolisation syndrome (PES) is a prevalent complication that occurs in patients following uterine artery embolisation (UAE) for the treatment of uterine fibroids. The aetiology of PES remains incompletely understood, although postulated to result secondary to tissue infarction resulting in release of inflammatory mediators. We followed PRISMA guidelines and performed a systematic review of studies of PES following UAE from inception to October 2022. Our published protocol was prospectively registered. Our search yielded 54 results. We reviewed 22 full texts, and nine articles were included. Observational studies comprised 6/9 relevant studies, with 5/9 retrospective design. The rate of PES was documented in 5/8 studies (excluding case report) with a reported incidence ranging from 4-34.6%. Five of the nine studies studies postulated that the aetiological basis of PES is inflammatory related. Further research is necessary to advance our understanding of PES to define the biological basis of the syndrome with more certainty and gain a consensus on peri-procedure management to reduce incidence and improve patient outcomes.
Databáze: MEDLINE
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