Protein Supplementation during Mid-Gestation Alters the Amino Acid Patterns, Hepatic Metabolism, and Maternal Skeletal Muscle Turnover of Pregnant Zebu Beef Cows.

Autor: Meneses JAM; Department of Animal Science, Universidade Federal de Lavras, Lavras 37200-900, MG, Brazil.; Department of Veterinary Medicine and Animal Science, Universidad de Ciencias Aplicadas y Ambientales, Cartagena 130001, Bolivar, Colombia., Nascimento KB; Department of Animal Science, Universidade Federal de Lavras, Lavras 37200-900, MG, Brazil., Galvão MC; Department of Animal Science, Universidade Federal de Lavras, Lavras 37200-900, MG, Brazil., Ramírez-Zamudio GD; Department of Animal Science, Universidade Federal de Lavras, Lavras 37200-900, MG, Brazil., Gionbelli TRS; Department of Animal Science, Universidade Federal de Lavras, Lavras 37200-900, MG, Brazil., Ladeira MM; Department of Animal Science, Universidade Federal de Lavras, Lavras 37200-900, MG, Brazil., Duarte MS; Department of Animal Bioscience, University of Guelph, Guelph, ON N1G 2W1, Canada., Casagrande DR; Department of Animal Science, Universidade Federal de Lavras, Lavras 37200-900, MG, Brazil., Gionbelli MP; Department of Animal Science, Universidade Federal de Lavras, Lavras 37200-900, MG, Brazil.
Jazyk: angličtina
Zdroj: Animals : an open access journal from MDPI [Animals (Basel)] 2022 Dec 16; Vol. 12 (24). Date of Electronic Publication: 2022 Dec 16.
DOI: 10.3390/ani12243567
Abstrakt: From 100 to 200 days of gestation, 52 cows carrying male ( n = 30) or female ( n = 22) fetuses were assigned to CON (basal diet-5.5% of CP, n = 26) or SUP (basal diet + protein supplement [40% CP, 3.5 g/kg BW]-12% of CP, n = 26) treatments. Glucose concentrations decreased at 200 ( p ≤ 0.01; CON = 46.9 and SUP = 54.7 mg/dL) and 270 days ( p ≤ 0.05; CON = 48.4 and SUP = 53.3 mg/dL) for CON compared to SUP. The same pattern occurred for insulin ( p ≤ 0.01). At parturition, the NEFA concentration was greater ( p = 0.01, 0.10 vs. 0.08 mmol/L) for CON than for SUP. Total AA increased in SUP ( p ≤ 0.03) at mid- and late-gestation compared to CON. At 200 days, CON dams carrying females had less essential AA ( p = 0.01) than cows carrying males. The SUP dams had greater expressions of protein synthesis markers, namely eIf4E and GSK3β ( p ≤ 0.04), at day 200 and of MuFR1 (protein degradation marker, p ≤ 0.04) at parturition. Supplemented cows had higher hepatic pyruvate carboxylase expressions ( p = 0.02). Therefore, PS alleviates the restriction overload on maternal metabolism.
Competing Interests: The authors declare no conflict of interest.
Databáze: MEDLINE
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