Genome-Wide Association Study for Body Conformation Traits and Fitness in Czech Holsteins.

Autor: Čítek J; Department of Genetics and Agricultural Biotechnology, Faculty of Agriculture, University of South Bohemia in České Budějovice, Studentská 1668, 370 05 České Budějovice, Czech Republic.; Veterinary Research Institute, Hudcova 296, 621 00 Brno, Czech Republic., Brzáková M; Institute of Animal Science, Přátelství 815, 104 00 Praha, Czech Republic., Bauer J; Czech Moravian Breeders' Corporation, Benešovská 123, 252 09 Hradištko, Czech Republic., Tichý L; Institute of Animal Science, Přátelství 815, 104 00 Praha, Czech Republic.; Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, 165 00 Praha, Czech Republic., Sztankóová Z; Institute of Animal Science, Přátelství 815, 104 00 Praha, Czech Republic., Vostrý L; Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, 165 00 Praha, Czech Republic., Steyn Y; Department of Animal and Dairy Science, University of Georgia, 425 River Road, Athens, GA 30602, USA.
Jazyk: angličtina
Zdroj: Animals : an open access journal from MDPI [Animals (Basel)] 2022 Dec 13; Vol. 12 (24). Date of Electronic Publication: 2022 Dec 13.
DOI: 10.3390/ani12243522
Abstrakt: The aim of this study was a genome-wide association study (GWAS) on conformation traits using 25,486 genotyped Czech Holsteins, with 35,227 common SNPs for each genotype. Linear trait records were collected between 1995 and 2020. The Interbull information from Multiple Across Country Evaluation (MACE) was included for bulls that mostly had daughter records in a foreign country. When using the Bonferroni correction, the number of SNPs that were either significant or approached the significance threshold was low-dairy capacity composite on BTA4, feet and legs composite BTA21, total score BTA10, stature BTA24, body depth BTA6, angularity BTA20, fore udder attachment BTA10. Without the Bonferroni correction, the total number of significant or near of significance SNPs was 32. The SNPs were localized on BTA1,2,4,5,6,7,8,18,22,25,26,28 for dairy capacity composite, BTA15,21 for feet and legs composite, BTA10 for total score, BTA24 stature, BTA6,23 body depth, BTA20 angularity, BTA2 rump angle, BTA9,10 rear legs rear view, BTA2,19 rear legs side view, BTA10 fore udder attachment, BTA2 udder depth, BTA10 rear udder height, BTA12 central alignment, BTA24 rear teat placement, BTA8,29 rear udder width. The results provide biological information for the improvement of body conformation and fitness in the Holstein population.
Databáze: MEDLINE
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