Spanish multidisciplinary consensus on the characteristics of severe asthma patients on biologic treatment who are candidates for at-home administration.

Autor: Cisneros-Serrano C; Pulmonology Department, Hospital Universitario La Princesa, Madrid, Spain. Electronic address: carol9199@yahoo.es., Rial MJ; Allergy Department, Complexo Hospitalario Universitario A Coruña, A Coruña, Spain., Gómez-Bastero-Fernández A; Pulmonology Department, Hospital Universitario Virgen Macarena, Seville, Spain., Igea JM; Clínica Alergoasma, Salamanca, Spain., Martínez-Meca A; Pulmonology Department Nurse, Hospital Universitario de La Princesa, Madrid, Spain., Fernández-Lisón LC; Hospital Pharmacy Department, Complejo Hospitalario Universitario de Cáceres, Cáceres, Spain., López-Carrasco V; Allergy Department Nurse, Hospital Universitario La Paz-Carlos III-Cantoblanco, Madrid, Spain., Villamañán-Bueno E; Pharmacy Department, Hospital Universitario La Paz, Madrid, Spain., Plá-Martí MJ; Allergy Department Nurse, Hospital Universitario La Fe, Valencia, Spain., Chiner E; Pulmonology Department, Hospital Universitario San Juan d'Alacant, Alicante, Spain.
Jazyk: angličtina
Zdroj: Revista clinica espanola [Rev Clin Esp (Barc)] 2023 Mar; Vol. 223 (3), pp. 154-164. Date of Electronic Publication: 2022 Dec 19.
DOI: 10.1016/j.rceng.2022.11.001
Abstrakt: Background and Objective: Biologic therapies are known to reduce exacerbations and improve severe uncontrolled asthma management. The at-home administration of biologics has increased during the COVID-19 pandemic, but the characteristics of severe uncontrolled asthma patients who may benefit from at-home administration of biologic therapy have yet to be identified.
Materials and Methods: This project is based on the Delphi method, designed to reach an expert consensus through a multidisciplinary scientific committee addressing the following questions: clinical characteristics, treatment adherence, patient or caregiver administration ability, patient self-care, relationship with the healthcare professional, patient preference, and access to the hospital.
Results: One hundred and thirty-one healthcare professionals (pulmonologists, allergists, nurses, and hospital pharmacists) completed two Delphi consensus questionnaires. Fourteen items were identified as priority characteristics, the first five being: 1. The patient follows the healthcare team's indications/recommendations to control their disease, 2. The patient is capable of detecting any deterioration in their disease and of identifying exacerbation triggers, 3. The patient receives biologic therapy and has stable disease with no vital risk, 4. The patient takes responsibility for their self-care, 5. The patient has occupational/educational obligations that prevent them from going to the hospital regularly.
Conclusion: Disease stability and control plus the ability to identify exacerbation triggers are the most important characteristics when opting for at-home administration for a patient with severe uncontrolled asthma on biologic therapy. These recommendations could be applicable in clinical practice.
(Copyright © 2022. Published by Elsevier España, S.L.U.)
Databáze: MEDLINE
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