Congenital Duodenal Obstruction: National Trends in Management and Outcomes during the Last Quarter of a Century in Norway.

Autor: Treider M; Department of General and Pediatric Surgery, Oslo University Hospital, Oslo, Norway., Granheim S; Department of Medicine, Norwegian University of Science and Technology, Trondheim, Trøndelag, Norway., Engebretsen AH; Department of General and Pediatric Surgery, Oslo University Hospital, Oslo, Norway., Pripp AH; Department of Biostatistics and Epidemiology, Oslo University Hospital, Oslo, Norway., Røkkum H; Department of General and Pediatric Surgery, Oslo University Hospital, Oslo, Norway.; Depratment of Clinical Medicine, University of Oslo Faculty of Medicine, Oslo, Norway., Skari H; Department of General and Pediatric Surgery, Oslo University Hospital, Oslo, Norway., Sæter T; Department of Medicine, Norwegian University of Science and Technology, Trondheim, Trøndelag, Norway.; Department of Pediatric Surgery, St. Olavs Hospital Trondheim University Hospital, Trondheim, Trøndelag, Norway., Bjørnland K; Department of General and Pediatric Surgery, Oslo University Hospital, Oslo, Norway.; Depratment of Clinical Medicine, University of Oslo Faculty of Medicine, Oslo, Norway.
Jazyk: angličtina
Zdroj: European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie [Eur J Pediatr Surg] 2023 Dec; Vol. 33 (6), pp. 503-509. Date of Electronic Publication: 2022 Dec 22.
DOI: 10.1055/a-2003-1920
Abstrakt: Introduction:  During the last quarter of a century, new surgical techniques in neonates have been introduced, and neonatal intensive care has developed. Few studies have explored the implementation of new techniques and if outcomes in neonates undergoing gastrointestinal surgery have improved in the last decades. Therefore, this study aimed to investigate possible changes in postoperative outcomes and surgical techniques in all neonates operated for congenital duodenal obstruction (CDO) 1995 to 2020 in Norway.
Material and Methods:  This is a national multicenter retrospective study of all neonates undergoing surgery for CDO in Norway from 1995 to 2020. Results from three periods (1995-2003, 2004-2012, and 2013-2020) were compared. The study was approved by the local data protection officers (2020/13386) and (2020/15125).
Results:  We included 186 patients: 41 in period 1 (1995-2003), 83 in period 2 (2004-2012), and 62 in period 3 (2013-2020). Seventy (38%) neonates had Down syndrome and 104 (62%) had additional malformations/disorders. Birth weight, gender, frequency of Down syndrome, and other malformations/disorders did not differ between the three periods. We observed an increased rate of prenatal diagnosis throughout the study period ( p  < 0.001). The only change in surgical technique was the increased use of transanastomotic feeding tubes ( p  < 0.001). Length of stay, postoperative complication rate, days with parenteral nutrition, and 30-day mortality rate were stable over time.
Conclusion:  Perioperative treatment and postoperative outcomes in neonates with CDO have been surprisingly unchanged during the last quarter of a century. Only an increased rate of prenatal diagnosis and more frequent use of transanastomotic feeding tubes were observed.
Competing Interests: None declared.
(Thieme. All rights reserved.)
Databáze: MEDLINE