Filtering Bleb Size in the Early Postoperative Period Affects the Long-term Surgical Outcome after Trabeculectomy.
| Autor: | Jang YK; Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea., Choi EJ; Department of Statistics and Data Science, Yonsei University, Seoul, Korea., Son DO; Department of Statistics and Data Science, Yonsei University, Seoul, Korea., Ahn BH; Department of Ophthalmology, Myung-Gok Eye Research Institute, Kim's Eye Hospital, Konyang University College of Medicine, Seoul, Korea., Han JC; Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.; Department of Medical Device, Management and Research, Samsung Advanced Institute for Health Sciences & Technology, Sungkyunkwan University, Seoul, Korea. |
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| Jazyk: | angličtina |
| Zdroj: | Korean journal of ophthalmology : KJO [Korean J Ophthalmol] 2023 Feb; Vol. 37 (1), pp. 53-61. Date of Electronic Publication: 2022 Dec 22. |
| DOI: | 10.3341/kjo.2022.0082 |
| Abstrakt: | Purpose: To investigate whether postoperative filtering bleb size affects the surgical outcome after trabeculectomy. Methods: In this study, we retrospectively reviewed 145 medically uncontrolled glaucoma patients with intraocular pressure (IOP) values >21 mmHg before surgery and data from ≥2 years of follow-up. Postoperative IOP, filtering bleb size including extent and height, and other clinical factors were measured after trabeculectomy. We divided bleb extent into quadrants and bleb height by 0.5 intervals of corneal thickness. The main outcome measure was surgical success. We confirmed complete success when the IOP was ≤21 mmHg and decreased by >20% from baseline without medication or additional procedures. Qualified success used the same criteria but allowed for medication or additional procedures. Cases with reoperation or two consecutive IOP measurements <6 mmHg were considered failures. Results: A total of 145 eyes of 145 patients was included. The average observation period was 30.8 ± 10.9 months. During multivariate Cox regression analysis, a larger extent of filtering bleb revealed significantly low hazard ratios in both complete and surgical success (0.509 and 0.494, respectively); however, there was no significant relationship between bleb height and surgical outcome. Conclusions: The extent of the filtering bleb was associated with surgical outcomes of trabeculectomy in glaucoma patients. |
| Databáze: | MEDLINE |
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