Kidney injury associated with COVID-19 infection and vaccine: A narrative review.

Autor:	Pacheco ICR; Division of Nephrology, University Hospital of the Federal University of Maranhão, São Luís, Brazil., Costa DMDN; Division of Nephrology, Hospital das Clínicas of the Federal University of Pernambuco, Recife, Brazil., Sousa DS; Division of Nephrology, University Hospital of the Federal University of Maranhão, São Luís, Brazil., Salgado Filho N; Division of Nephrology, University Hospital of the Federal University of Maranhão, São Luís, Brazil., Silva GEB; Division of Nephrology, University Hospital of the Federal University of Maranhão, São Luís, Brazil.; Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil., Neves PDMM; Division of Nephrology, University of São Paulo, São Paulo, Brazil.; Nephrology and Dialysis Center, Oswaldo Cruz German Hospítal, São Paulo, Brazil.
Jazyk:	angličtina
Zdroj:	Frontiers in medicine [Front Med (Lausanne)] 2022 Dec 05; Vol. 9, pp. 956158. Date of Electronic Publication: 2022 Dec 05 (Print Publication: 2022).
DOI:	10.3389/fmed.2022.956158
Abstrakt:	The respiratory tract is the main infection site for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), resulting in many admissions to intensive care centers in several countries. However, in addition to lung involvement, kidney injury caused by the novel coronavirus has proven to be a significant factor related to high morbidity and mortality, alarming experts worldwide. The number of deaths has drastically reduced with the advent of large-scale immunization, highlighting the importance of vaccination as the best way to combat the pandemic. Despite the undeniable efficacy of the vaccine, the renal side effects associated with its use deserve to be highlighted, especially the emergence or reactivation of glomerulopathies mentioned in some case reports. This study aimed to identify the main renal morphological findings correlated with COVID-19 infection and its vaccination, seeking to understand the pathophysiological mechanisms, main clinical features, and outcomes. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2022 Pacheco, Costa, Sousa, Salgado Filho N, Silva and Neves.)
Databáze:	MEDLINE
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