Re-irradiation of Pediatric Medulloblastoma: A Case Report and Systematic Review.
| Autor: | Giakoumettis G; Medical Physics, Aristotle University of Thessaloniki, Thessaloniki, GRC., Mantzavinou A; Medicine, Barts and The London School of Medicine and Dentistry, London, GBR., Moschos G; Department of Radiation Oncology, AHEPA University Hospital, Thessaloniki, GRC., Giakoumettis D; Neurosurgery, Queen's Hospital, Romford, London, GBR., Capizzello A; Department of Radiation Oncology, AHEPA University Hospital, Thessaloniki, GRC. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2022 Nov 16; Vol. 14 (11), pp. e31585. Date of Electronic Publication: 2022 Nov 16 (Print Publication: 2022). |
| DOI: | 10.7759/cureus.31585 |
| Abstrakt: | Despite the optimal treatment given to children with medulloblastoma, many relapses are seen after combining treatments. Re-irradiation is part of salvage therapy for children who relapse and might provide long-term disease control. Nevertheless, it is challenging because there is a concern about exceeding radiation tolerances and late treatment toxicities. Re-irradiation is an option for many brain tumors, including medulloblastoma in children. This study presents a case of recurrent medulloblastoma treated with re-irradiation. A systematic review of the literature provided up-to-date data on the re-irradiation of medulloblastoma in children. This study aims to contribute to the scarce literature on the treatment strategy, which may help improve patients' outcomes. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2022, Giakoumettis et al.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|