Assessment of prescribing pattern of drugs and completeness of prescriptions as per the World Health Organization prescribing indicators in various Indian tertiary care centers: A multicentric study by Rational Use of Medicines Centers-Indian Council of Medical Research network under National Virtual Centre Clinical Pharmacology activity.

Autor: Joshi R; Department of Pharmacology, Post Graduate Institute of Medical Education and Research, Chandigarh, India., Medhi B; Department of Pharmacology, Post Graduate Institute of Medical Education and Research, Chandigarh, India., Prakash A; Department of Pharmacology, Post Graduate Institute of Medical Education and Research, Chandigarh, India., Chandy S; Department of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, Tamil Nadu, India., Ranjalkar J; Department of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, Tamil Nadu, India., Bright HR; Department of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, Tamil Nadu, India., Basker J; Department of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, Tamil Nadu, India., Govindraj L; Department of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, Tamil Nadu, India., Chugh PK; Vardhman Mahavir Medical College, New Delhi, India., Tripathi CD; Vardhman Mahavir Medical College, New Delhi, India., Badyal DK; Department of Pharmacology, Christian Medical College, Ludhiana, Punjab, India., Balakrishnan S; Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, India., Jhaj R; Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, India., Shukla AK; Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, India., Atal S; Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, India., Najmi A; Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, India., Banerjee A; Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, India., Kamat S; Department of Pharmacology and Therapeutics, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India., Tripathi RK; Department of Pharmacology and Therapeutics, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India., Shetty YC; Department of Pharmacology and Therapeutics, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India., Parmar U; Department of Pharmacology and Therapeutics, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India., Rege N; Department of Pharmacology and Therapeutics, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India., Dikshit H; Department of Pharmacology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India., Mishra H; Department of Pharmacology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India., Roy SS; Department of Pharmacology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India., Chatterjee S; Department of Pharmacology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India., Hazra A; Department of Pharmacology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India., Bhattacharya M; Department of Pharmacology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India., Das D; Department of Pharmacology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India., Trivedi N; Department of Pharmacology, Government Medical College, Baroda, Gujarat, India., Shah P; Department of Pharmacology, Government Medical College, Baroda, Gujarat, India., Chauhan J; Department of Pharmacology, Government Medical College, Baroda, Gujarat, India., Desai C; Department of Pharmacology, B.J. Medical College, Ahmedabad, Gujarat, India., Gandhi AM; Department of Pharmacology, B.J. Medical College, Ahmedabad, Gujarat, India., Patel PP; Department of Pharmacology, B.J. Medical College, Ahmedabad, Gujarat, India., Shah S; Department of Pharmacology, B.J. Medical College, Ahmedabad, Gujarat, India., Sheth S; Department of Pharmacology, B.J. Medical College, Ahmedabad, Gujarat, India., Raveendran R; Department of Pharmacology, Jawaharlal Institute of Post Medical Education and Research, Puducherry, India., Mathaiyan J; Department of Pharmacology, Jawaharlal Institute of Post Medical Education and Research, Puducherry, India., Manikandan S; Department of Pharmacology, Jawaharlal Institute of Post Medical Education and Research, Puducherry, India., Jeevitha G; Department of Pharmacology, Jawaharlal Institute of Post Medical Education and Research, Puducherry, India., Gupta P; Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India., Sarangi SC; Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India., Yadav HN; Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India., Singh S; Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India., Kaushal S; Department of Pharmacology, Dayanand Medical college and Hospital, Ludhiana, Punjab, India., Arora S; Department of Pharmacology, Dayanand Medical college and Hospital, Ludhiana, Punjab, India., Gupta K; Department of Pharmacology, Dayanand Medical college and Hospital, Ludhiana, Punjab, India., Jain S; Department of Pharmacology, Dayanand Medical college and Hospital, Ludhiana, Punjab, India., Cherian JJ; Indian Council of Medical Research, New Delhi, India., Chatterjee NS; Indian Council of Medical Research, New Delhi, India., Kaul R; Indian Council of Medical Research, New Delhi, India., Kshirsagar NA; Indian Council of Medical Research, New Delhi, India.
Jazyk: angličtina
Zdroj: Indian journal of pharmacology [Indian J Pharmacol] 2022 Sep-Oct; Vol. 54 (5), pp. 321-328.
DOI: 10.4103/ijp.ijp_976_21
Abstrakt: Objective: The rational use of medicines as per the World Health Organization (WHO) should be practiced globally. However, data regarding the completeness of the prescriptions and their rational use is lacking from developing countries like India. Thus, the aim of this study was to assess the prescribing patterns of drugs and completeness of prescriptions as per WHO core drug use and complementary indicators to provide real-life examples for the Indian Council of Medical Research (ICMR) online prescribing skill course for medical graduates.
Methods: Prescriptions of the patients, fulfilling inclusion criteria, attending Outpatient Departments of various specialties of tertiary care hospitals, were collected by thirteen ICMR Rational use of medicines centers located in tertiary care hospitals, throughout India. Prescriptions were evaluated for rational use of medicines according to the WHO guidelines and for appropriateness as per standard treatment guidelines using a common protocol approved by local Ethics committees.
Results: Among 4838 prescriptions, an average of about three drugs (3.34) was prescribed to the patients per prescription. Polypharmacy was noted in 83.05% of prescriptions. Generic drugs were prescribed in 47.58% of the prescriptions. Further, antimicrobials were prescribed in 17.63% of the prescriptions and only 4.98% of prescriptions were with injectables. During the prescription evaluation, 38.65% of the prescriptions were incomplete due to multiple omissions such as dose, duration, and formulation.
Conclusion: Most of the parameters in the present study were out of the range of WHO-recommended prescribing indicators. Therefore, effective intervention program, like training, for the promotion of rational drug use practice was recommended to improve the prescribing pattern of drugs and the quality of prescriptions all over the country.
Competing Interests: None
Databáze: MEDLINE
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