Videodermoscopic Changes of the Hair in Vitiligo Lesions in Relation to Disease Duration.

Autor:	Anbar T; Department of Dermatology and Venereology, Faculty of Medicine, Al-Minya University, Al-Minya, Egypt., Abdelraouf H; Department of Dermatology and Venereology, Faculty of Medicine, Al-Minya University, Al-Minya, Egypt., Abd Elfattah Afify A; Department of Dermatology, and Venereology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Ragaie MH; Department of Dermatology and Venereology, Faculty of Medicine, Al-Minya University, Al-Minya, Egypt., Eid AA; Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University, Alexandria, Egypt., Moneib H; Department of Dermatology, and Venereology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Jazyk:	angličtina
Zdroj:	Dermatology practical & conceptual [Dermatol Pract Concept] 2022 Oct 01; Vol. 12 (4), pp. e2022163. Date of Electronic Publication: 2022 Oct 01 (Print Publication: 2022).
DOI:	10.5826/dpc.1204a163
Abstrakt:	Introduction: Vitiligo is an acquired disease of complex pathogenesis, in which the immunologic attack to the skin and hair follicle melanocytes leads to areas of depigmentation and leukotrichia, respectively. Objectives: To study the dermoscopic features of the hair changes in vitiligo lesions in comparison to perilesional control areas and in relation to disease duration. Methods: Forty-seven patients with both old and recent vitiligo lesions were included. Dermoscopic features of hair within the lesions were examined and compared to those in perilesional non depigmented skin of the same patient. Results: Hair density (P < 0.001), terminal hair rate (P = 0.011), terminal to vellus hair ratio (P = 0.029) and mean hair shaft thickness (P = 0.031) were significantly decreased, whereas vellus hair rate (P = 0.011) was significantly increased in old vitiligo lesions compared to their respective control areas. The frequency of broken hair was significantly higher in old lesions (P < 0.001), while that of upright re-growing hair was significantly higher in recent lesions (P = 0.016). Conclusions: Hair involvement in vitiligo lesions is not only limited to the development of leukotrichia. Other subtle changes in hair density, anagen and telogen hair rates, and mean hair thickness can be detected. These changes may serve as objective clues to the duration of the lesions. Competing Interests: Competing interests: None. (©2022 Anbar et al.)
Databáze:	MEDLINE
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