Differential Associations of Frailty with the Incidence of Mild and Severe Disabilities in Older Adults: A 3-Year Cohort Study.

Autor:	Hagiyama A; Department of Epidemiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.; Division of Physical Medicine and Rehabilitation, Okayama University Hospital, Okayama, Japan., Takao S; Department of Epidemiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan., Matsuo R; Department of Epidemiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan., Yorifuji T; Department of Epidemiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Jazyk:	angličtina
Zdroj:	Annals of geriatric medicine and research [Ann Geriatr Med Res] 2022 Dec; Vol. 26 (4), pp. 309-315. Date of Electronic Publication: 2022 Dec 19.
DOI:	10.4235/agmr.22.0097
Abstrakt:	Background: Frailty is associated with the incidence of disability in older adults; however, few studies have investigated differences in the association of frailty with mild and severe disabilities according to Japanese long-term care insurance certification. This study separately investigated the associations between frailty and the incidence of mild and severe disabilities. Methods: This 3-year retrospective cohort study included community-dwelling adults in Okayama City aged ≥65 years. We assessed frailty status using the Kihon Checklist and defined the outcomes as mild and severe disabilities according to long-term care insurance certifications. We applied multinomial logistic regression analysis to investigate the association between frailty and the incidence of mild and severe disabilities. Results: The analysis included a total of 36,043 participants. For mild disability, the odds ratios (ORs) comparing frail to robust and prefrail to robust were 3.85 (95% confidence interval [CI], 3.36-4.42) and 1.82 (95% CI, 1.58-2.10), respectively. Similarly, the corresponding ORs for severe disability were 4.35 (95% CI, 3.55-5.34) and 1.78 (95% CI, 1.43-2.21), respectively. In the age-stratified analysis of mild disability, the pre-old group (aged 65-74 years) with frail showed a higher association than the old-age group (aged ≥75 years) with frail. Regarding severe disability, the older group with frailty showed a higher association than the pre-old group with frailty. Conclusion: The results showed that both prefrail and frail were associated with the incidence of mild and severe disabilities, with different patterns of association between the pre-old and old age groups.
Databáze:	MEDLINE
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