Cell viability and physicochemical effects of different concentrations of bismuth trioxide in a mineral trioxide aggregate cement.

Autor: Padrón-Alvarado K; Dental Materials and Biomaterials Research Laboratory, Postgraduate Studies and Research Division, Faculty of Dentistry, National Autonomous University of México., García-Mendoza LA; Dental Materials and Biomaterials Research Laboratory, Postgraduate Studies and Research Division, Faculty of Dentistry, National Autonomous University of México., Ramírez-Ortega JP; Dental Materials and Biomaterials Research Laboratory, Postgraduate Studies and Research Division, Faculty of Dentistry, National Autonomous University of México., Rodríguez-Chavéz JA; Department of Integral Dental Clinics, University Center for Health Sciences, University of Guadalajara., Moyaho-Bernal MDLA; Dental Materials and Biomaterials Laboratory Faculty of Stomatology, Meritorious Autonomous University of Puebla., Arreguín-Cano JA; Health of the State of Guerrero., Hoz-Rodríguez LA; Periodontal Biology and Mineralized Tissue Laboratory, Postgraduate Studies and Research Division, School of Dentistry, National Autonomous University of México., Wintergerst A; Division of Postgraduate Studies and Research, School of Dentistry, National Autonomous University of México., Arenas-Alatorre JA; Central Microscopy Laboratory, Institute of Physics, National Autonomous University of México., Flores-Ledesma A; Dental Materials and Biomaterials Laboratory Faculty of Stomatology, Meritorious Autonomous University of Puebla.
Jazyk: angličtina
Zdroj: Journal of oral science [J Oral Sci] 2023 Jan 11; Vol. 65 (1), pp. 10-14. Date of Electronic Publication: 2022 Dec 16.
DOI: 10.2334/josnusd.22-0139
Abstrakt: Purpose: To evaluate the effect of three concentrations of bismuth trioxide (Bi 2 O 3 ) on the biological and physicochemical properties of an experimental mineral trioxide aggregate-type (MTA-type) cement at different time points.
Methods: Three experimental groups with white Portland cement containing 15, 20, or 25 wt% of Bi 2 O 3 were assessed. Cellular proliferation in human periodontal ligament fibroblasts was evaluated with an MTT assay. Radiopacity, dimensional stability, pH, and compressive strength were evaluated at different time points.
Results: Bismuth trioxide induced cell proliferation in the Bi15 and Bi25 groups in a time-dependent manner; pH was similar in all groups. Compressive strength was associated with time and bismuth concentration. Bi25 had significantly contracted at day 7 and expanded at day 14 (ANOVA P < 0.05, post hoc Tukey test P < 0.05).
Conclusion: A higher Bi 2 O 3 concentration had a negative effect on the physical properties of the cement at all time points.
Databáze: MEDLINE
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