Acute Complications of Sickle Cell Disease in Children Under 5 Years at a Level II Hospital.
| Autor: | Lage J; Hospital Professor Doutor Fernando Fonseca, Amadora, Lisboa, Portugal., Monteiro B; Hospital Professor Doutor Fernando Fonseca, Amadora, Lisboa, Portugal., Costa A; Hospital Professor Doutor Fernando Fonseca, Amadora, Lisboa, Portugal., Mendes IF; Hospital Professor Doutor Fernando Fonseca, Amadora, Lisboa, Portugal., Ferreira T; Hospital Professor Doutor Fernando Fonseca, Amadora, Lisboa, Portugal., Loureiro HC; Hospital Professor Doutor Fernando Fonseca, Amadora, Lisboa, Portugal. |
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| Jazyk: | angličtina |
| Zdroj: | Global pediatric health [Glob Pediatr Health] 2022 Dec 08; Vol. 9, pp. 2333794X221141356. Date of Electronic Publication: 2022 Dec 08 (Print Publication: 2022). |
| DOI: | 10.1177/2333794X221141356 |
| Abstrakt: | The aim of this study was to characterize the acute complications that required hospitalization in children under 5 years with Sickle Cell Disease. The population included 70 patients, 64% of African ascendency and 95.7% homozygotic for the HbS. We analyzed data from 337 hospitalizations. The first hospitalization occurred before 12 months in 38.6% and the average hospital admission per child was 3.92. The mean duration per hospitalization was 5.36 days. The most common diagnosis was vaso-occlusive crisis (36.8%) followed by fever, upper airway infections, bacterial pneumonia and splenic sequestration. Hemoglobin values at admission were between 6 and 7 g/dL in 22.3%, with 44.2% requiring at least 1 blood transfusion. There are several acute complications of SCD, being vaso-occlusive crisis the most common. Splenic sequestration generally occurs during the first 2 years and is associated with the need of transfusion. They represent a significant burden, with each child spending approximately 3 weeks hospitalized. Competing Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. (© The Author(s) 2022.) |
| Databáze: | MEDLINE |
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