Early time-restricted eating affects weight, metabolic health, mood, and sleep in adherent completers: A secondary analysis.

Autor: Steger FL; Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA.; Division of Endocrinology, Diabetes and Clinical Pharmacology, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA., Jamshed H; Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA.; Department of Integrated Sciences and Mathematics, Habib University, Karachi, Pakistan., Bryan DR; Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA., Richman JS; Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA., Warriner AH; Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA., Hanick CJ; Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA., Martin CK; Ingestive Behavior Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA., Salvy SJ; Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, Los Angeles, California, USA., Peterson CM; Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Jazyk: angličtina
Zdroj: Obesity (Silver Spring, Md.) [Obesity (Silver Spring)] 2023 Feb; Vol. 31 Suppl 1, pp. 96-107. Date of Electronic Publication: 2022 Dec 14.
DOI: 10.1002/oby.23614
Abstrakt: Objective: Data are mixed on whether intermittent fasting improves weight loss and cardiometabolic health. Here, the effects of time-restricted eating (TRE) in participants who consistently adhered ≥5 d/wk every week were analyzed.
Methods: Ninety patients aged 25 to 75 years old with obesity were randomized to early TRE (eTRE; 8-hour eating window from 07:00 to 15:00) or a control schedule (≥12-hour window) for 14 weeks. A per-protocol analysis of weight loss, body composition, cardiometabolic health, and other end points was performed.
Results: Participants who adhered to eTRE ≥5 d/wk every week had greater improvements in body weight (-3.7 ± 1.2 kg; p = 0.003), body fat (-2.8 ± 1.3 kg; p = 0.04), heart rate (-7 ± 3 beats/min; p = 0.02), insulin resistance (-2.80 ± 1.36; p = 0.047), and glucose (-9 ± 5 mg/dL; p = 0.047) relative to adherers in the control group. They also experienced greater improvements in mood, including fatigue and anger; however, they self-reported sleeping less and taking longer to fall asleep.
Conclusions: For those who can consistently adhere at least 5 d/wk, eTRE is a valuable approach for improving body weight, body fat, cardiometabolic health, and mood. Further research is needed to determine whether eTRE's effects of shortening sleep but reducing fatigue are healthful or not.
(© 2022 The Obesity Society.)
Databáze: MEDLINE
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