The Key Role of Glutathione Compared to Curcumin in the Management of Systemic Lupus Erythematosus: A Systematic Review.

Autor:	Ravi N; Internal Medicine and Neurology, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA., Choday S; Internal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA., Shantha Kumar V; Internal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA., Kc A; Internal Medicine/Family Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA., Parisapogu A; Infectious Diseases, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA., Ojinna BT; Internal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA., Tran HH; Internal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA., Sherpa ML; Internal Medicine/Neurology, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA., Shrestha N; Pathology and Internal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA., Mohammed L; Internal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2022 Nov 10; Vol. 14 (11), pp. e31324. Date of Electronic Publication: 2022 Nov 10 (Print Publication: 2022).
DOI:	10.7759/cureus.31324
Abstrakt:	In recent years, many documented cases of systemic lupus erythematosus (SLE) have been on the rise. The complicated pathophysiology of the disease makes it challenging to manage. Two databases, PubMed and Google Scholar, have a detailed screening using keywords and Medical Subject Heading (MeSH) combinations. The words are "Systemic Lupus Erythematosus OR SLE OR Lupus," "Glutathione," and "Curcumin." Articles had a detailed process of screening and quality appraisal. Using the English language as a primary filtering parameter, papers over the last 20 years, dating from 2002 to 2022, are the basis of this review. We reviewed all possible human studies documenting the use of curcumin and glutathione for treating SLE. A total of 15 articles are part of this systematic review. Curcumin and glutathione can act as potent drugs for treating lupus. Curcumin can be a more promising alternative since it operates on various pathways and is a more easily accessible source. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2022, Ravi et al.)
Databáze:	MEDLINE
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