Quantitative assessment of depolarization by the retinal pigment epithelium in healthy and glaucoma subjects measured over a large field of view.

Autor: Motschi AR; Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria., Schwarzhans F; Center for Medical Statistics, Informatics and Intelligent Systems, Medical University of Vienna, Vienna, Austria.; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria., Desissaire S; Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria., Steiner S; Department of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria., Bogunović H; Christian Doppler Laboratory for Artificial Intelligence in Retina, Medical University of Vienna, Vienna, Austria., Roberts PK; Department of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria., Vass C; Department of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria., Hitzenberger CK; Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria., Pircher M; Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2022 Dec 13; Vol. 17 (12), pp. e0278679. Date of Electronic Publication: 2022 Dec 13 (Print Publication: 2022).
DOI: 10.1371/journal.pone.0278679
Abstrakt: We present measurements of depolarization introduced by the retinal pigment epithelium (RPE) over a 45° field of view using polarization sensitive optical coherence tomography. A detailed spatial distribution analysis of depolarization caused by the RPE is presented in a total of 153 subjects including both healthy and diseased eyes. Age and sex related differences in the depolarizing character of the RPE are investigated.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2022 Motschi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje