Differences in the Relationships Between Muscle Strength, Muscle Mass, Balance Function, and Quality of Life for Middle-Aged and Older Breast Cancer Survivors.

Autor: Morishita S; Fukushima Medical University, Fukushima, Japan., Kasahara R; Kita-Fukushima Medical Center, Fukushima, Japan., Yamamoto Y; Kita-Fukushima Medical Center, Fukushima, Japan., Jinbo R; Kita-Fukushima Medical Center, Fukushima, Japan., Takano A; Kita-Fukushima Medical Center, Fukushima, Japan., Yasuda M; Kita-Fukushima Medical Center, Fukushima, Japan., Tsubaki A; Niigata University of Health and Welfare, Niigata, Japan., Aoki O; Shijonawate Gakuen University, Osaka, Japan., Fu JB; University of Texas MD Anderson Cancer Center, Houston, TX, USA., Tsuji T; Keio University School of Medicine, Tokyo, Japan.
Jazyk: angličtina
Zdroj: Integrative cancer therapies [Integr Cancer Ther] 2022 Jan-Dec; Vol. 21, pp. 15347354221138574.
DOI: 10.1177/15347354221138574
Abstrakt: Purpose: The purpose of this study was to investigate the differences in muscle strength, muscle mass, balance function, and quality of life (QOL) among middle-aged breast cancer survivors (BCSs) and older BCSs.
Methods: The study included 53 middle-aged (<65 years old) BCSs and 49 older (≥65 years old) BCSs. Muscle strength was evaluated via handgrip and knee extensor strength, and muscle mass was assessed using a body composition test. Balance function was assessed using the Timed Up and Go test and the body sway test. QOL was assessed using the Medical Outcome Study 36-item Short-Form Health Survey.
Results: The older BCSs had significantly lower right grip strength, right knee extension strength, and muscle mass ( P  < .05) than the middle-aged BCSs. In addition, the body sway test showed that older BCSs had a significant increase in the length of center of pressure compared to middle-aged BCSs ( P  < .05). Older BCSs showed significantly lower physical functioning subscales in QOL compared to middle-aged BCSs ( P  < .05). The associations among muscle strength, muscle mass and QOL were more significantly observed in the older BCSs ( P  < .05). Furthermore, a significant correlation between QOL and balance function was observed in the older BCSs, but not in the middle-aged BCSs ( P  < .05).
Conclusion: There may be associations among muscle strength, muscle mass, balance and QOL in older BCSs, but not in middle-aged BCSs. We believe that the findings of this study will be relevant in the context of planning rehabilitation for older BCSs.
Databáze: MEDLINE