Cognitive performance among older adults with psychotic depression compared to non-psychotic depression.

Autor: Vermeulen T; University of Antwerp, Collaborative Antwerp Psychiatric Research Institute, Universiteitsplein 1, Wilfijk, 2610, Belgium. Electronic address: toverme@gmail.com., Sabbe BG; University of Antwerp, Collaborative Antwerp Psychiatric Research Institute, Universiteitsplein 1, Wilfijk, 2610, Belgium., Østergaard SD; Department of Clinical Medicine, Department of Affective Disorders, Aarhus University, Denmark., Giltay EJ; University of Antwerp, Collaborative Antwerp Psychiatric Research Institute, Universiteitsplein 1, Wilfijk, 2610, Belgium; Leiden University Medical Center, the Netherlands., Van der Mast RC; University of Antwerp, Collaborative Antwerp Psychiatric Research Institute, Universiteitsplein 1, Wilfijk, 2610, Belgium; Leiden University Medical Center, the Netherlands.
Jazyk: angličtina
Zdroj: Psychiatry research [Psychiatry Res] 2023 Jan; Vol. 319, pp. 114996. Date of Electronic Publication: 2022 Nov 29.
DOI: 10.1016/j.psychres.2022.114996
Abstrakt: It remains unclear whether psychotic depression (PD) compared to non-psychotic depression (non-PD) among older adults is associated with poorer cognitive performance. For inpatients (60+) with a major depressive episode, cognitive performance in PD and non-PD (categorical) were compared as well as the relationship between symptom severity for depression and psychosis (dimensional) and cognition. Of 90 participants (on average 72.7 years old; range 60-92), 64% were female. The severity of depressive- and psychotic symptoms are both negatively associated with cognitive functioning among older adults with depression. This is of relevance for the treatment of this vulnerable group of patients.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2022. Published by Elsevier B.V.)
Databáze: MEDLINE