Clinical Findings Predicting Posttraumatic Endophthalmitis after Repair of Open Globe Injuries.

Autor:	Abouammoh MA; Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Alsarhani WK; Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Aljasser A; Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Gikandi PW; Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Al-Mezaine HS; Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Abu El-Asrar AM; Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.; Dr. Nasser Al-Rashid Research Chair in Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Jazyk:	angličtina
Zdroj:	Ocular immunology and inflammation [Ocul Immunol Inflamm] 2024 Aug; Vol. 32 (6), pp. 912-918. Date of Electronic Publication: 2022 Dec 12.
DOI:	10.1080/09273948.2022.2150226
Abstrakt:	Background: To evaluate risk factors for developing endophthalmitis after repair of open globe injuries. Methods: Retrospective chart analysis of 1303 patients from May 1996 till December 2019. Results: All patients received prophylactic intravenous broad-spectrum antibiotics for 5-7 days. Endophthalmitis was clinically suspected in 37 (2.8%) eyes and was culture proven in 14 of these eyes (1.1%). Univariate analysis identified poor initial visual acuity at presentation, rural setting of injury, contaminated wound and lens injury as significant predictors for the development of clinically suspected endophthalmitis. Intravitreal antibiotics at the time of primary repair in eyes with high-risk characteristics decreased risk of developing endophthalmitis (OR: 2.28;95% CI,1.07-4.86; p = .033). Conclusions: Poor initial visual acuity, rural setting of injury, contaminated wound, and lens injury increased risk of suspected posttraumatic endophthalmitis. Prophylactic intravitreal antibiotics at the time of primary repair in eyes with high-risk characteristics reduced the risk of posttraumatic endophthalmitis.
Databáze:	MEDLINE
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