[Transcranial alternating current stimulation to modulate oscillations in pain disorders].

Autor: Wandrey JD; Klinik für Anästhesiologie mit Schwerpunkt operative Intensivmedizin, Campus Charité Mitte und Campus Virchow-Klinikum, Charité - Universitätsmedizin Berlin, Gliedkörperschaft der Freien Universität Berlin, der Humboldt Universität zu Berlin und des Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Deutschland., Kandić M; Institut für Neuropsychologie und Klinische Psychologie, Zentralinstitut für Seelische Gesundheit, Medizinische Fakultät Mannheim, Universität Heidelberg, J5, 68159, Mannheim, Deutschland., Haberbosch L; Klinik für Endokrinologie, Diabetologie und Stoffwechselmedizin, Charité - Universitätsmedizin Berlin, Gliedkörperschaft der Freien Universität Berlin, der Humboldt Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Deutschland.; BIH Biomedical Innovation Academy, BIH Charité Junior Digital Clinician Scientist Program, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland., Serian A; Institut für Neuropsychologie und Klinische Psychologie, Zentralinstitut für Seelische Gesundheit, Medizinische Fakultät Mannheim, Universität Heidelberg, J5, 68159, Mannheim, Deutschland. angela.serian@zi-mannheim.de.
Jazyk: němčina
Zdroj: Schmerz (Berlin, Germany) [Schmerz] 2023 Aug; Vol. 37 (4), pp. 281-289. Date of Electronic Publication: 2022 Dec 12.
DOI: 10.1007/s00482-022-00684-4
Abstrakt: Background: Chronic pain is a common health problem, for which the treatment is complex and challenging. Non-invasive brain stimulation techniques, specifically transcranial alternating current stimulation (tACS), show promise as a well-tolerated new therapeutic modality with few side effects. This is supported by growing evidence of an association between altered neuronal oscillations and chronic pain. However, to date, only a handful of studies with variable methodology have evaluated tACS for potential applicability to patients with chronic pain.
Objectives: Presentation and discussion of the evidence thus far, evaluation of a potential therapeutic benefit for chronic pain patients.
Materials and Methods: Literature search in MEDLINE, Embase, Cochrane Library, and Google Scholar databases.
Results: To date, tACS for chronic pain therapy has been investigated in only three studies with very different methodological approaches and quality.
Discussion: These data currently do not provide sufficient evidence for the therapeutic use of tACS for chronic pain therapy. Future studies may address the question of a therapeutic benefit of tACS for this indication utilizing improved stimulation techniques and considering existing recommendations for the design and conduct of tACS studies.
(© 2022. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)
Databáze: MEDLINE
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