Patent foramen ovale: diagnostic evaluation and the role of device closure.

Autor: Gonnah AR; University of Liverpool School of Medicine, Liverpool, UK.; joint first authors., Bharadwaj MS; University of Liverpool School of Medicine, Liverpool, UK m.s.bharadwaj@student.liverpool.ac.uk.; joint first authors., Nassar H; University of Liverpool School of Medicine, Liverpool, UK., Abdelaziz HK; Blackpool Teaching Hospitals NHS Foundation Trust, Blackpool, UK., Roberts DH; Blackpool Teaching Hospitals NHS Foundation Trust, Blackpool, UK and honorary senior clinical lecturer, University of Liverpool, Liverpool, UK.
Jazyk: angličtina
Zdroj: Clinical medicine (London, England) [Clin Med (Lond)] 2022 Sep; Vol. 22 (5), pp. 441-448.
DOI: 10.7861/clinmed.2022-0040
Abstrakt: Although seemingly benign, the presence of a patent foramen ovale (PFO) may play an important role in the pathophysiology of disease, specifically a paradoxical embolism leading to cryptogenic stroke. The European Society of Cardiology recently published guidelines detailing how PFOs are associated with paradoxical embolism and how they are diagnosed and managed. This review guides physicians in the diagnostic and referral process to a multidisciplinary team involved in PFO closure. It reviews the clinical trials comparing device closure with medical therapy and highlights the current NHS England commissioning process on PFO management. Finally, we give an overview of other conditions where PFO device closure may need to be considered.
(© Royal College of Physicians 2022. All rights reserved.)
Databáze: MEDLINE