Bridging the genomic data gap in Africa: implications for global disease burdens.

Autor: Omotoso OE; Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria., Teibo JO; Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Nigeria. johnteibo@usp.br.; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil. johnteibo@usp.br., Atiba FA; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Oladimeji T; Department of Zoology, University of Ibadan, Ibadan, Nigeria., Adebesin AO; Department of Biochemistry, Cancer Genomics Lab, Covenant University, Ota, Nigeria., Babalghith AO; Medical Genetics Department, College of Medicine, Umm al-qura University, Makkah, Saudi Arabia.
Jazyk: angličtina
Zdroj: Globalization and health [Global Health] 2022 Dec 09; Vol. 18 (1), pp. 103. Date of Electronic Publication: 2022 Dec 09.
DOI: 10.1186/s12992-022-00898-2
Abstrakt: This paper highlights the gap in the use of genomic data of Africans for global research efforts for disease cures. Genomic data represents an important tool used in disease research for understanding how diseases affect several populations and how these differences can be harnessed for the development of effective cures especially vaccines that have an impact at the genetic level e.g., RNA vaccines.This paper then provides a review of global genomic data status where three continents are reported to be the major contributor of genomic data to repositories used for disease research and the development of vaccines and medicines around the world.We reviewed the most recently published information about genetic data inclusiveness of populations, explaining how genomic data of Africans is lacking in global research efforts that cater towards the eradication of pandemics via the development of vaccines and other cures. We also discuss the implication of this non-inclusiveness for global disease burdens and indicate where changes need to be made in the last part of the paper.Lastly, the entire centers on some general policy recommendations to fully include African genomic data in such global genetic repositories. These recommendations can be implemented in African countries to improve genetic data collection, storage, and usage policies.
(© 2022. The Author(s).)
Databáze: MEDLINE
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