Therapeutic Efficacy of Shexiang Baoxin Pill Combined with Exercise in Patients with Heart Failure with Preserved Ejection Fraction: A Single-Center, Double-Blind, Randomized Controlled Trial.
Autor: | Liu SP; Nanjing Drum Tower Hospital, Clinical College of Nanjing University of Chinese Medicine, Nanjing, 210008, China.; Department of Rehabilitation, College of Acupuncture and Moxibustion and Massage Health Preservation and Rehabilitation, Nanjing University of Chinese Medicine, Nanjing, 210023, China., Zhou JG; Division of Cardiovascular Rehabilitation, Ruian Hospital of Traditional Chinese Medicine, Ruian, Zhejiang Province, 325299, China., Jin Y; Department of Rehabilitation, College of Acupuncture and Moxibustion and Massage Health Preservation and Rehabilitation, Nanjing University of Chinese Medicine, Nanjing, 210023, China., Guo Y; Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China., Zhou SW; Division of Cardiovascular Rehabilitation, Ruian Hospital of Traditional Chinese Medicine, Ruian, Zhejiang Province, 325299, China., Lin ML; Nanjing Drum Tower Hospital, Clinical College of Nanjing University of Chinese Medicine, Nanjing, 210008, China.; Department of Rehabilitation, College of Acupuncture and Moxibustion and Massage Health Preservation and Rehabilitation, Nanjing University of Chinese Medicine, Nanjing, 210023, China., Zhang J; Division of Cardiovascular Rehabilitation, Ruian Hospital of Traditional Chinese Medicine, Ruian, Zhejiang Province, 325299, China., Wang XN; Division of Cardiovascular Rehabilitation, Ruian Hospital of Traditional Chinese Medicine, Ruian, Zhejiang Province, 325299, China., Guan XF; Division of Cardiovascular Rehabilitation, Ruian Hospital of Traditional Chinese Medicine, Ruian, Zhejiang Province, 325299, China., Wang L; Nanjing Drum Tower Hospital, Clinical College of Nanjing University of Chinese Medicine, Nanjing, 210008, China. wanglei@njucm.edu.cn.; Department of Rehabilitation, College of Acupuncture and Moxibustion and Massage Health Preservation and Rehabilitation, Nanjing University of Chinese Medicine, Nanjing, 210023, China. wanglei@njucm.edu.cn. |
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Jazyk: | angličtina |
Zdroj: | Chinese journal of integrative medicine [Chin J Integr Med] 2023 Feb; Vol. 29 (2), pp. 99-107. Date of Electronic Publication: 2022 Dec 09. |
DOI: | 10.1007/s11655-022-3627-3 |
Abstrakt: | Objective: To evaluate the therapeutic efficacy of Shexiang Baoxin Pill combined with exercise in heart failure patients with preserved ejection fraction (HFpEF). Methods: Sixty patients with HFpEF were randomly divided into group A (n=20), receiving Shexiang Baoxin Pill combined with home-based exercise training based on conventional drugs for 12 weeks; group B (n=20), receiving conventional drugs combined with home-based exercise training for 12 weeks; and group C (n=20), receiving conventional drug treatment only. Peak oxygen uptake (peakVO Results: After the 12-week intervention, patients in group C showed significant declines in peakVO Conclusions: Exercise training improved exercise tolerance, sleep quality and quality of life (QoL) in patients with HFpEF. Notably, Shexiang Baoxin Pill played an active role in sleep quality and QoL of patients with HFpEF. (The trial was registered in the Chinese Clinical Trial Registry (No. ChiCTR2100054322)). (© 2022. The Chinese Journal of Integrated Traditional and Western Medicine Press and Springer-Verlag GmbH Germany, part of Springer Nature.) |
Databáze: | MEDLINE |
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