Autor: |
Wang YY; Department of Neurology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China., Liu XJ; Department of Neurology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China., Pei LL; Department of Neurology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China., Liu K; Department of Neurology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China., Hu RY; Department of Neurology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China., Wang X; Department of Neurology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China., Sun WX; Department of Neurology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China., Zhang LY; Department of Neurology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China., Liang J; Department of Neurology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China., Xu YM; Department of Neurology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China., Song B; Department of Neurology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China. |
Abstrakt: |
Objective: To investigate the prevalence of atrial cardiomyopathy in patients with different types of acute ischemic stroke and its relationship with cryptogenic stroke. Methods: Patients with acute ischemic stroke within 7 days of onset who were admitted to the Department of Neurology of the First Affiliated Hospital of Zhengzhou University from January to September 2019 were prospectively and consecutively enrolled. All included patients were classified according to TOAST classification of ischemic stroke. Chi-square test was used to compare the prevalence of atrial cardiomyopathy among patients with different TOAST classifications. Multivariate logistic regression model was used to analyze the related factors of cryptogenic stroke. Results: A total of 1 098 patients with acute ischemic stroke were enrolled in the study, including 661 males and 437 females, with a median age [ M ( Q 1 , Q 3 )] of 61 (53, 68) years. The prevalence of atrial cardiomyopathy in patients with cryptogenic stroke[53.5% (46/86)] was higher than that in patients with large artery atherosclerosis [38.0%(63/166), P =0.018] and small vessel occlusion [19.4%(37/191), P <0.001], but was lower than that of patients in the cardioembolic group [97.3% (72/74), P< 0.001]. Multivariate logistic regression analysis showed that atrial cardiomyopathy was an associated factor for cryptogenic stroke ( OR =2.945, 95% CI : 1.766-4.911, P <0.001). Conclusions: Atrial cardiomyopathy is associated with cryptogenic stroke. The prevalence of atrial cardiomyopathy in patients with cryptogenic stroke is higher than that in patients with large artery atherosclerosis and small vessel occlusion, but lower than that in patients with cardiac embolism. |