Simplified acute physiology score II and Mannheim peritonitis index are associated with in-hospital mortality in patients with abdominal sepsis admitted to ICU.

Autor:	Sánchez-Díaz JS; Unidad de Cuidados Intensivos, Hospital de Especialidades Número 14, Instituto Mexicano del Seguro Social (IMSS), Unidad Médica de Alta Especialidad (UMAE), Veracruz. Mexico., Escarraman-Martínez D; Departamento de Anestesiología, Centro Médico Nacional 'La Raza', Instituto Mexicano del Seguro Social (IMSS), Mexico City. Mexico., Guerrero-Gutiérrez MA; Unidad de Cuidados Intensivos, Baja Hospital and Medical Center, Baja California. Mexico.; Departamento de Anestesiología Bariátrica, Baja Hospital and Medical Center, Baja California. Mexico., Meza-Comparán HD; Dirección de Investigación, Instituto Nacional de Geriatría, Mexico City. Mexico., Mancilla-Galindo J; División de Posgrado, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), Mexico City. Mexico., Peniche-Moguel KG; Unidad de Cuidados Intensivos, Hospital de Especialidades Número 14, Instituto Mexicano del Seguro Social (IMSS), Unidad Médica de Alta Especialidad (UMAE), Veracruz. Mexico., González-Escudero EA; Unidad de Cuidados Intensivos, Hospital de Especialidades Número 14, Instituto Mexicano del Seguro Social (IMSS), Unidad Médica de Alta Especialidad (UMAE), Veracruz. Mexico., Carpio-Orantes LD; Unidad de Cuidados Intensivos, Hospital General de Zona No. 71, IMSS, Veracruz. Mexico., Monares-Zepeda E; Unidad de Cuidados Intensivos, Medical Center ABC, Mexico City. Mexico., Perez-Nieto OR; Unidad de Cuidados Intensivos, Hospital General San Juan del Rio, Querétaro. Mexico., Zamarrón-López EI; Unidad de Cuidados Intensivos, Hospital General Regional No. 6, IMSS, Ciudad Madero, Tamaulipas. Mexico., Deloya-Tomas E; Unidad de Cuidados Intensivos, Hospital General San Juan del Rio, Querétaro. Mexico., Calyeca-Sanchez V; Unidad de Cuidados Intensivos, Hospital de Especialidades Número 14, Instituto Mexicano del Seguro Social (IMSS), Unidad Médica de Alta Especialidad (UMAE), Veracruz. Mexico., Kammar-García A; Dirección de Investigación, Instituto Nacional de Geriatría, Mexico City. Mexico.; Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional (IPN), México City. Mexico.
Jazyk:	angličtina
Zdroj:	Cirugia y cirujanos [Cir Cir] 2022; Vol. 90 (S2), pp. 81-91.
DOI:	10.24875/CIRU.22000219
Abstrakt:	Objective: The objective of this study was to assess the association and interaction of laboratory parameters, Simplified Acute Physiology Score II (SAPSII), Modified Shock Index (MSI), and Mannheim Peritonitis Index (MPI) with in-hospital mortality. Material and Methods: We conducted a single-center case-control study. Adult patients with abdominal sepsis were included from May 2015 to May 2020. Baseline characteristics, laboratory parameters, SAPSII, MSI, and MPI scores at admission were collected. A principal component (PC) analysis was applied to evaluate variable interactions. In-hospital mortality risk was determined through logistic regression models. Results: One hundred and twenty-seven patients were identified, 60 of which were included for analyses. Non-survivors (48.4%) had a higher frequency of hypertension, lactate and MPI, and lower BE and alactic BE levels. Eight PCs were obtained, PC1 being a linear combination of pH, AG, cAG, alactic BE, bicarbonate, and BE. MPI (OR = 9.87, 95% CI: 3.07-36.61, p = 0.0002), SAPSII (OR = 1.07, 95% CI: 1.01-1.14, p = 0.01), and PC1 (OR = 2.13, 95% CI: 1.12-4.76, p = 0.04) were significantly associated with mortality in univariate analysis, while MPI (OR = 10.1, 95% CI: 3.03-40.06, p = 0.0003) and SAPSII (OR = 1.07, CI95%: 1.01-1.14, p = 0.02) remained significant after adjusting for age and sex. Conclusion: MPI and SAPSII were associated with mortality, although the interaction of laboratory parameters was not. (Copyright: © 2022 Permanyer.)
Databáze:	MEDLINE
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