Dietary supplements for intestinal inflammation.

Autor: Kiani AK; MAGI Euregio, Bolzano, Italy., Bonetti G; MAGI'S LAB, Rovereto (TN), Italy., Donato K; MAGI Euregio, Bolzano, Italy., Bertelli M; MAGI Euregio, Bolzano, Italy.; MAGI'S LAB, Rovereto (TN), Italy.; MAGISNAT, Peachtree Corners (GA), USA.
Jazyk: angličtina
Zdroj: Journal of preventive medicine and hygiene [J Prev Med Hyg] 2022 Oct 17; Vol. 63 (2 Suppl 3), pp. E214-E220. Date of Electronic Publication: 2022 Oct 17 (Print Publication: 2022).
DOI: 10.15167/2421-4248/jpmh2022.63.2S3.2763
Abstrakt: Intestinal inflammation leads to various chronic diseases, collectively known as inflammatory bowel disease (IBD). IBD mainly affects the large intestine, but it can also affect the gastrointestinal tract as a whole. Its major symptoms are pain, diarrhea, and weight loss, and it is usually associated with deficiencies of both macro- and micronutrients. Unluckily, after some time the body develops resistance against the already available drugs: thus, many patients fail to maintain remission, which is achieved in less than 50% of cases. Diet is a major determinant of gut inflammation. An unbalanced diet can affect the gut microbiota and cause dysbiosis, which is related to a dysregulated host immune response. The Mediterranean Diet its renowned for its anti-inflammatory effects and for preventing dysbiosis. In order to improve management and treatment of intestinal inflammatory diseases, it should become common practice to integrate the patient's diet with dietary supplements with anti-inflammatory effects (probiotics, butyrate, phosphatidylcholine, lactoferrin, palmitoylethanolamide, silymarin, and omega 3), which maintain the stability of the intestinal microbial cohort and strengthen the mucosal barrier, thus preventing or soothing IBD symptoms. Dietary supplements may help fight the high costs, the adverse side effects, and the recurrent relapses typical of drug use.
(©2022 Pacini Editore SRL, Pisa, Italy.)
Databáze: MEDLINE
Externí odkaz: