Short-term outcomes of COVID-19 in pregnant women unvaccinated for SARS-CoV-2 in the first, second, and third trimesters: a retrospective study.

Autor:	Guleroglu FY; MD. Perinatologist, Department of Obstetrics and Gynecology, Haseki Training and Research Hospital affiliated with Health Sciences University, Sultangazi, Istanbul, Turkey., Atalmis HA; MD. Obstetrician and Gynecologist, Department of Obstetrics and Gynecology, Haseki Training and Research Hospital affiliated with Health Sciences University, Sultangazi, Istanbul, Turkey., Bafali IO; MD. Obstetrician and Gynecologist, Department of Obstetrics and Gynecology, Haseki Training and Research Hospital affiliated with Health Sciences University, Sultangazi, Istanbul, Turkey., Dikdere GB; MD. Obstetrician and Gynecologist, Department of Obstetrics and Gynecology, Haseki Training and Research Hospital affiliated with Health Sciences University, Sultangazi, Istanbul, Turkey., Dikdere I; MD. Obstetrician and Gynecologist, Department of Obstetrics and Gynecology, Haseki Training and Research Hospital affiliated with Health Sciences University, Sultangazi, Istanbul, Turkey., Ekmez M; MD. Obstetrician and Gynecologist, Department of Obstetrics and Gynecology, Haseki Training and Research Hospital affiliated with Health Sciences University, Sultangazi, Istanbul, Turkey., Kaban A; MD. Gynecologic Oncologist, Department of Obstetrics and Gynecology, Haseki Training and Research Hospital affiliated with Health Sciences University, Sultangazi, Istanbul, Turkey., Karasabanoglu F; MD. Obstetrician and Gynecologist, Department of Obstetrics and Gynecology, Haseki Training and Research Hospital affiliated with Health Sciences University, Sultangazi, Istanbul, Turkey., Atas BS; MD. Obstetrician and Gynecologist, Department of Obstetrics and Gynecology, Haseki Training and Research Hospital affiliated with Health Sciences University, Sultangazi, Istanbul, Turkey., Selvi E; MD. Obstetrician and Gynecologist, Department of Obstetrics and Gynecology, Haseki Training and Research Hospital affiliated with Health Sciences University, Sultangazi, Istanbul, Turkey., Sumnu G; MD. Obstetrician and Gynecologist, Department of Obstetrics and Gynecology, Haseki Training and Research Hospital affiliated with Health Sciences University, Sultangazi, Istanbul, Turkey., Topaktas M; MD. Obstetrician and Gynecologist, Department of Obstetrics and Gynecology, Haseki Training and Research Hospital affiliated with Health Sciences University, Sultangazi, Istanbul, Turkey., Dayan MY; MD. Obstetrician and Gynecologist, Department of Obstetrics and Gynecology, Haseki Training and Research Hospital affiliated with Health Sciences University, Sultangazi, Istanbul, Turkey., Dogu SY; MD. Obstetrician and Gynecologist, Department of Obstetrics and Gynecology, Haseki Training and Research Hospital affiliated with Health Sciences University, Sultangazi, Istanbul, Turkey., Cetin A; MD, PhD. Perinatologist, Department of Obstetrics and Gynecology, Haseki Training and Research Hospital affiliated with Health Sciences University, Sultangazi, Istanbul, Turkey.
Jazyk:	angličtina
Zdroj:	Sao Paulo medical journal = Revista paulista de medicina [Sao Paulo Med J] 2022 Oct 28; Vol. 141 (4), pp. e2022323. Date of Electronic Publication: 2022 Oct 28 (Print Publication: 2022).
DOI:	10.1590/1516-3180.2022.0323.R1.19082022
Abstrakt:	Background: Coronavirus disease 2019 (COVID-19) may be asymptomatic or symptomatic in pregnant women. Compared to non-pregnant reproductive-aged women, symptomatic individuals appear to have a higher risk of acquiring severe illness sequelae. Objectives: We assessed the clinical and laboratory characteristics and outcomes of pregnant COVID-19 patients unvaccinated for severe acute respiratory syndrome coronavirus 2 according to the trimester of pregnancy. Design and Setting: This was a retrospective observational study conducted in a tertiary-level hospital in Turkey. Methods: This retrospective study reviewed the clinical and laboratory characteristics and outcomes of 445 pregnant COVID-19 patients hospitalized during the first, second, and third trimesters of pregnancy and 149 other pregnant women as controls in a tertiary center from April 2020 to December 2021. All participants were unvaccinated. Results: Overall, the study groups were comparable in terms of baseline clinical pregnancy characteristics. There was no clear difference among the study participants with COVID-19 in the first, second, and third trimesters of pregnancy. However, a considerably high number of clinical and laboratory findings revealed differences that were consistent with the inflammatory nature of the disease. Conclusions: The study results reveal the importance of careful follow-up of hospitalized cases as a necessary step by means of regular clinical and laboratory examinations in pregnant COVID-19 patients. With further studies, after implementing vaccination programs for COVID-19 in pregnant women, these data may help determine the impact of vaccination on the outcomes of pregnant COVID-19 patients.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu