Age-varying Associations of Depressive Symptoms and Heavy Episodic Drinking Throughout Adulthood Among People with HIV and Receiving care in Cameroon Within a National "treat all" Policy.

Autor: Lancaster KE; College of Public Health, The Ohio State University, 1841 Neil Avenue, 43210, Columbus, OH, USA. lancaster.111@osu.edu., Remch M; Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, USA., Edmonds A; Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, USA., Ajeh R; Clinical Research Education Networking and Consultancy, Yaounde, Cameroon., Dzudie A; Clinical Research Education Networking and Consultancy, Yaounde, Cameroon., Adedimeji A; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA., Nash D; City University of New York, New York, NY, USA., Anastos K; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA., Yotebieng M; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA., Yone-Pefura EW; Jamot Hospital, Yaounde, Cameroon., Nsame D; Bamenda Regional Hospital, Bamenda, Cameroon., Parcesepe AM; Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Jazyk: angličtina
Zdroj: AIDS and behavior [AIDS Behav] 2023 Jul; Vol. 27 (7), pp. 2070-2078. Date of Electronic Publication: 2022 Dec 06.
DOI: 10.1007/s10461-022-03939-4
Abstrakt: Comorbid depression and heavy episodic drinking (HED) may threaten the success of "treat all" policies in sub-Saharan Africa as the population of people with HIV (PWH) ages. We investigated associations between depressive symptoms and heavy episodic drinking (HED) and the extent the relationship differed across ages among PWH receiving HIV care in Cameroon. We conducted a retrospective analysis of 18-60-year-old PWH on antiretroviral therapy in Cameroon from January 2016 to March 2020. Age-varying effect modelling was conducted to assess associations between depressive symptoms and HED across ages and by gender. Prevalence of depression and HED was highest at ages 20 and 25, respectively. After age 25, the magnitude of the association between depressive symptoms and HED was significant and increased until age 30 (aOR: 1.88, 95% CI: 1.48, 2.39), with associations remaining significant until age 55 (aOR: 1.64, 95% CI: 1.17, 2.29). Women had more variability and higher magnitudes of associations between depressive symptoms and HED than men. The interrelationship between depressive symptoms and HED was significant throughout most of adulthood for PWH receiving HIV care in Cameroon. Understanding age and gender trends in these associations can guide integration efforts in HIV care settings.
(© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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