ATM Regulation of the Cohesin Complex Is Required for Repression of DNA Replication and Transcription in the Vicinity of DNA Double-Strand Breaks.
| Autor: | Bass TE; Department of Pharmacology and Cancer Biology and Duke Cancer Institute, Duke University, Durham, North Carolina., Fleenor DE; Department of Pharmacology and Cancer Biology and Duke Cancer Institute, Duke University, Durham, North Carolina., Burrell PE; Department of Pharmacology and Cancer Biology and Duke Cancer Institute, Duke University, Durham, North Carolina., Kastan MB; Department of Pharmacology and Cancer Biology and Duke Cancer Institute, Duke University, Durham, North Carolina. |
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| Jazyk: | angličtina |
| Zdroj: | Molecular cancer research : MCR [Mol Cancer Res] 2023 Mar 01; Vol. 21 (3), pp. 261-273. |
| DOI: | 10.1158/1541-7786.MCR-22-0399 |
| Abstrakt: | Implications: Multiple members of the cohesin complex are involved in the regulation of DNA replication and transcription in the vicinity of DNA double-strand breaks and their role(s) are regulated by the ATM kinase. (©2022 American Association for Cancer Research.) |
| Databáze: | MEDLINE |
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