Subcutaneous panniculitis-like T-cell lymphoma: an unusual cause of right thigh hypertrophy.

Autor: Ayesh Haj Yousef MH; Department of Medicine, Jordan University of Science and Technology, Irbid, Jordan ayeshmahmoud@hotmail.com., Al-Khatib SM; Deapertment of Pathology and Microbiology, Jordan University of Science and Technology, Irbid, Jordan., Khasawneh RA; Department of Diagnostic Radiology and Nuclear Medicine, Jordan University of Science and Technology, Irbid, Jordan., Rahabneh L; Department of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Jazyk: angličtina
Zdroj: BMJ case reports [BMJ Case Rep] 2022 Dec 02; Vol. 15 (12). Date of Electronic Publication: 2022 Dec 02.
DOI: 10.1136/bcr-2022-253469
Abstrakt: A man in his mid-20s presented with a painless swelling over his right thigh, which had been progressively increasing over 3 years. He underwent an excisional biopsy for the same, which showed reactive lymphadenopathy. Since the last year and a half, he developed a lower abdominal wall swelling with mild redness over it. In addition, over the last few months before presentation to haematology outpatient clinic, he experienced bouts of fever, night sweats, anorexia, weight loss and right inguinal lymphadenopathy. On examination, splenomegaly was identified. In view of the patients' symptoms, he underwent a positron emission tomography scan, which showed hypermetabolic activity in the subcutaneous tissue sparing the lymph nodes and spleen. A deep skin punch biopsy taken from his right thigh was consistent with the diagnosis of subcutaneous panniculitis-like T-cell lymphoma αβ T-cell phenotype. The patient was treated successfully with oral steroids and on routine follow-up, he is in remission for 5 years.
Competing Interests: Competing interests: None declared.
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Databáze: MEDLINE