Phlebovirus diversity in ticks from livestock in arid ecologies in Kenya.

Autor: Ogola EO; International Centre of Insect Physiology and Ecology (icipe), P.O. Box 30772-00100, Nairobi, Kenya; Department of Zoology and Entomology, University of Pretoria, Private Bag 20, Pretoria 0028, South Africa., Kopp A; Institute of Virology, Charité Universitätsmedizin Berlin, Corporate Member of Free University Berlin, Humboldt-University Berlin, and Berlin Institute of Health, Chariteplatz 1, 10117 Berlin, Germany., Bastos ADS; Department of Zoology and Entomology, University of Pretoria, Private Bag 20, Pretoria 0028, South Africa., Slothouwer I; Institute of Virology, Charité Universitätsmedizin Berlin, Corporate Member of Free University Berlin, Humboldt-University Berlin, and Berlin Institute of Health, Chariteplatz 1, 10117 Berlin, Germany., Omoga DCA; International Centre of Insect Physiology and Ecology (icipe), P.O. Box 30772-00100, Nairobi, Kenya., Osalla J; International Centre of Insect Physiology and Ecology (icipe), P.O. Box 30772-00100, Nairobi, Kenya., Sang R; International Centre of Insect Physiology and Ecology (icipe), P.O. Box 30772-00100, Nairobi, Kenya., Torto B; International Centre of Insect Physiology and Ecology (icipe), P.O. Box 30772-00100, Nairobi, Kenya; Department of Zoology and Entomology, University of Pretoria, Private Bag 20, Pretoria 0028, South Africa., Junglen S; Institute of Virology, Charité Universitätsmedizin Berlin, Corporate Member of Free University Berlin, Humboldt-University Berlin, and Berlin Institute of Health, Chariteplatz 1, 10117 Berlin, Germany. Electronic address: sandra.junglen@charite.de., Tchouassi DP; International Centre of Insect Physiology and Ecology (icipe), P.O. Box 30772-00100, Nairobi, Kenya. Electronic address: dtchouassi@icipe.org.
Jazyk: angličtina
Zdroj: Ticks and tick-borne diseases [Ticks Tick Borne Dis] 2023 Jan; Vol. 14 (1), pp. 102087. Date of Electronic Publication: 2022 Nov 20.
DOI: 10.1016/j.ttbdis.2022.102087
Abstrakt: Phleboviruses are emerging pathogens of public health importance. However, their association with ticks is poorly described, particularly in Africa. Here, adult ticks infesting cattle, goats and sheep were collected in two dryland pastoralist ecosystems of Kenya (Baringo and Kajiado counties) and were screened for infection with phleboviruses. Ticks mainly belonged to the species Rhipicephalus appendiculatus, Hyalomma impeltatum, and Hyalomma rufipes. A fragment of the RNA-dependent RNA polymerase (RdRp) gene was identified in thirty of 671 tick pools, of which twenty-nine were from livestock sampled in Baringo county. Phylogenetic analyses revealed that twenty-five sequences were falling in three clades within the group of tick-associated phleboviruses. The sequences of the three clades showed nucleotide distances 8%, 19% and 22%, respectively, to previously known viruses suggesting that these sequence fragments may belong to three distinct viruses. Viruses of the group of tick-associated phleboviruses have been found in several countries and continents but so far have not been associated with disease in humans or animals. In addition, five sequences were found to group with the sandfly-associated phleboviruses Bogoria virus, Perkerra virus and Ntepes virus recently detected in the same region. Further studies are needed to investigate the transmission and maintenance cycles of these viruses, as well as to assess their potential to infect vertebrates.
Competing Interests: Declaration of Competing Interest The authors declare no conflicts of interest. The funders had no role in the study design, data collection and interpretation, or the decision to submit the work for publication.
(Copyright © 2022. Published by Elsevier GmbH.)
Databáze: MEDLINE
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