Brain metastasis from a thoracic myxofibrosarcoma: A case report and literature review.

Autor:	Ferreira Neto ODC; Department of Medicine, Catholic University of Pernambuco, Recife, Brazil., Bezerra RB; Department of Oncology, Hospital Memorial São José, Recife, Brazil., Silva RPDS; Department of Medicine, Catholic University of Pernambuco, Recife, Brazil., Silva MHR; Department of Medicine, Catholic University of Pernambuco, Recife, Brazil., de Alencar Neto JF; Department of Medicine, Unifacisa University Center, Campina Grande, Brazil., Lopes AJM; Department of Neurosurgery, Real Hospital Português, Recife, Brazil.
Jazyk:	angličtina
Zdroj:	Surgical neurology international [Surg Neurol Int] 2022 Nov 18; Vol. 13, pp. 537. Date of Electronic Publication: 2022 Nov 18 (Print Publication: 2022).
DOI:	10.25259/SNI_717_2022
Abstrakt:	Background: Myxofibrosarcoma (MFS) is a type of sarcoma that mainly affects elderly people; it represents only 5% of all sarcomas and shows no line of differentiation. Intracranial MFS is a rare condition. At present, limited data exist regarding brain metastasis from MFS. This article reports a case of MFS and reviews the literature regarding MFS metastasis. Case Description: We report a case of brain metastasis from chest wall MFS. The patient was diagnosed with an anterior thoracic MFS and underwent surgery and radiotherapy. One year later, he noticed a tumor on his left shoulder, and more than 1 year thereafter, bilateral lung metastasis was observed. Twelve months after lung metastasis, he presented to the emergency department and underwent contrast-enhanced magnetic resonance imaging, which demonstrated a left frontal tumor suggestive of brain metastasis. Since the main hypothesis was a sarcoma metastasis at the location close to the left motor area, and the patient had a good Karnofsky performance scale, the patient underwent neuronavigation-guided surgery. After surgery, the patient developed Grade III hemiparesis and aphasia. Brain tumor histopathology confirmed a malignant neoplasm with osteosarcomatous differentiation and metastasis from MFS. Conclusion: We report a rare case of MFS metastasis. To the best of our knowledge, this is the eighth case of intracerebral metastasis from MFS. Competing Interests: There are no conflicts of interest. (Copyright: © 2022 Surgical Neurology International.)
Databáze:	MEDLINE
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