Case report and review of the literature of primary central nervous system lymphoma of the fourth ventricle.

Autor:	Kojima Y; Department of Neurosurgery, Osaka Metropolitan University, Osaka, Japan., Nakajo K; Department of Neurosurgery, Osaka Metropolitan University, Osaka, Japan., Ichinose T; Department of Neurosurgery, Osaka Metropolitan University, Osaka, Japan., Morikawa Y; Department of Hematology, Sumitomo Hospital, Osaka, Japan., Osawa M; Department of Pathology, Osaka Metropolitan University, Osaka, Japan., Goto T; Department of Neurosurgery, Osaka Metropolitan University, Osaka, Japan.
Jazyk:	angličtina
Zdroj:	Surgical neurology international [Surg Neurol Int] 2022 Nov 11; Vol. 13, pp. 529. Date of Electronic Publication: 2022 Nov 11 (Print Publication: 2022).
DOI:	10.25259/SNI_654_2022
Abstrakt:	Background: Primary central nervous system lymphoma of the fourth ventricle is very rare. We present a case of primary central nervous system lymphoma originating from the fourth ventricle and review cases reported in the literature. Case Description: A 54-year-old man with no previous medical history presented with headache and nausea. Magnetic resonance imaging showed a homogeneously enhancing tumor in the fourth ventricle and obstructive hydrocephalus. We performed biopsy of the tumor, which was diagnosed pathologically as diffuse large B-cell lymphoma. Although the tumor disappeared after 5 cycles of R-MPV regimen, the patient required repeated ventricular drainage and finally received a ventriculoperitoneal shunt. Complete response was achieved after 2 cycles of high-dose cytarabine chemotherapy with an autologous peripheral blood stem cell transplant. There was no sign of recurrence at 20 months after biopsy. Conclusion: Morbidity arising due to radical resection/radiotherapy of resistant primary central nervous system lymphoma originating from the fourth ventricle could be prevented by ventriculoperitoneal shunting with chemotherapy and autologous blood stem cell transplantation. Competing Interests: There are no conflicts of interest. (Copyright: © 2022 Surgical Neurology International.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu